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" Molecular neurosurgery with targeted toxins / "
edited by Ronald G. Wiley and Douglas A. Lappi
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BL
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| Record Number
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695222
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| Doc. No
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b517411
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| Title & Author
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Molecular neurosurgery with targeted toxins /\ edited by Ronald G. Wiley and Douglas A. Lappi
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| Publication Statement
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Totowa, N.J. :: Humana Press,, c2005
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| Page. NO
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xi, 311 p. :: ill. ;; 24 cm
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| ISBN
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1588291995 (alk. paper)
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: 159259896X (e-isbn)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Introduction to molecular neurosurgery / Ronald G. Wiley and Douglas A. Lappi -- Ribosome-inactivating proteins / Fiorenzo Stirpe -- Biochemical, physiological, and behavioral characterizations of the cholinergic basal forebrain lesion produced by 192 IgG-saporin / Jerene J. Waite -- Basal forebrain cholinergic lesion by 192 IgG-saporin: a tool to assess the consequences of cortical cholinergic dysfunction in Alzheimers disease / Reinhard Schliebs -- 192 IgG-saporin-induced partial cortical cholinergic deafferentation as a model for determining the interactions between brain aging and neurodevelopmental defects in the cortical cholinergic input system / Martin Sarter and John P. Bruno -- Exploring the role of acetylcholine in primate cognition using Me20.4 IgG-saporin / Rosalind M. Ridley and Harry F. Baker -- Cortical cholinergic deafferentation induces A-beta deposition: towards a physiologic animal model of Alzheimer's disease / Thomas G. Beach ... [et al.] -- Chemical dissection of brain glucoregulatory circuitry / Sue Ritter ... [et al.] -- Cardiovascular deficits after lesions of C1 adrenergic neurons with a saporin-based immunotoxin / Patrice G. Guyenet, Ruth L. Stornetta, and Ann M. Schreihofer -- Saporin conjugates and pain / Ronald G. Wiley and Douglas A. Lappi -- The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness / Carlos Blanco-Centurion ... [et al.] -- Isolectin I-B4-mediated cytotoxic targeting of sensory neurons / Lucy Vulchanova and Christopher N. Honda -- B fragment of cholera toxin conjugated to saporin / Peter T. O'hara, Kanwarjit Kelley, and Luc Jasmin
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Antibody-toxin conjugates-- Therapeutic use
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Drug targeting
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Neurotoxic agents-- Therapeutic use
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Immunotoxins-- therapeutic use
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Antibodies, Monoclonal-- therapeutic use
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Cholinergic Fibers-- metabolism
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Neurobiology-- methods
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Neurons-- pathology
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| Dewey Classification
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616.8/0471
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| LC Classification
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RC347.5.M65 2005
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| NLM classification
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QW 630.6.I3M718 2005
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| Added Entry
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Lappi, Douglas A
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Wiley, Ronald G.,1947-
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