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" Camptothecins in cancer therapy / "
edited by Val R. Adams and Thomas G. Burke
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BL
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| Record Number
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695247
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| Doc. No
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b517436
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| Title & Author
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Camptothecins in cancer therapy /\ edited by Val R. Adams and Thomas G. Burke
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| Publication Statement
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Totowa, N.J. :: Humana Press,, c2005
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| Series Statement
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Cancer drug discovery and development
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| Page. NO
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xiii, 460 p. :: ill. (some col.) ;; 24 cm
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| ISBN
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1588290271 (hardcover : alk. paper)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Mechanism of action of topoisomerase I poisons / Leroy F. Liu and Shyamal D. Desai -- Crystallographic insight into the mechanism of drug-induced topoisomerase I DNA damage / Alex B. Burgin, Jr., Bart L. Staker, and Lance Stewart -- Inhibitors of topoisomerase I function / Sidney M. Hecht -- Cytotoxic mechanisms of the topoisomerase I inhibitors / Yves Pommier ... [et al.] -- Biochemical and genetic analyses of DNA topoisomerase I-mediated DNA damage / Robert C.A.M. Van Waardenburg and Mary-Ann Bjornsti -- Preclinical models for evaluating topoisomerase-I targeted drugs / Aarti S. Juvekar ... [et al.] -- Mechanisms of resistance to camptothecins / Zeshaan A. Rasheed and Eric H. Rubin -- Recent advances in camptothecin drug design and delivery strategies / Thomas G. Burke ... [et al.] -- Clinical experience with 9-aminocamptothecin: lessons for new drug development / Chris H. Takimoto -- Clinical studies of rubitecan (9-nitro 20(s) camptothecin) / Hilary Hewes, Judith A. Smith, and Claire Verschraegen -- Irinotecan: current clinical status and pharmacological aspects / Laurent P. Rivory -- Clinical experience with topotecan / Aimee K. Bence and Val R. Adams -- The clinical development of lurtotecan: experience with water-soluble and liposomal forms / Keith T. Flaherty ... [et al.] -- Preclinical and clinical development of dx-8951f (exatecan mesylate): a hexacyclic camptothecin analog / Eric K. Rowinsky -- Camptothecins in the treatment of primary brain tumors / Clinton F. Stewart, Markos Leggas, and Henry S. Friedman -- Camptothecins in the treatment of lung cancer / Pankaj Kumar ... [et al.] -- Use of camptothecins in the treatment of leukemia and related disorders / Bejamin M.F. Mow and Scott H. Kaufmann
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| Subject
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Camptothecin
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| Subject
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Cancer-- Chemotherapy
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| LC Classification
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RC271.C35C345 2005
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RC271.C35C345 2005
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| Added Entry
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Adams, Val R
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Burke, Thomas G.,PhD
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