| Document Type
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BL
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| Record Number
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699360
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| Doc. No
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b521549
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| Title & Author
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Therapeutic oligonucleotides /\ edited by Jens Kurreck
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| Publication Statement
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Cambridge :: Royal Society of Chemistry,, c2008
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| Series Statement
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RSC biomolecular sciences
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| Page. NO
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xvii, 343 p. :: ill. (some col.) ;; 24 cm
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| ISBN
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0854041168 (hbk.)
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: 9780854041169 (hbk.)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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The role of backbone modifications in oligonucleotide-based strategies -- Genasense (G3139) : an antisense Bcl-2 oligodeoxyribonucleotide with substantial clinical activity and a complex mechanism of action -- Antisense morpholino oligomers and their peptide conjugates -- Peptide-peptide nucleic acid conjugates for modulation of gene expression -- Locked nucleic acid: properties and therapeutic aspects -- Immune stimulatory oligonucleotides -- Decoy oligodeoxynucleotides to treat inflammatory diseases -- AS1411 : development of an anticancer aptamer -- Spiegelmer NOX-E36 for renal diseases -- Strategies for the delivery of oligonucleotides in vivo -- Lipid-mediated in vivo delivery of small interfering RNAs -- Vector-mediated and viral delivery of short hairpin RNAs -- Development of an RNAi-based gene therapy against HIV-1 -- RNA based therapies for treatment of HIV infection
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| Subject
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Oligonucleotides-- Therapeutic use
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| Dewey Classification
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615.31
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| LC Classification
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RM666.N87T44 2008
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| Added Entry
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Kurreck, Jens
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