|
" Structure and mechanism in protein science : "
Alan Fersht
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
704437
|
| Doc. No
|
:
|
b526626
|
| Main Entry
|
:
|
Fersht, Alan,1943-
|
| Title & Author
|
:
|
Structure and mechanism in protein science : : a guide to enzyme catalysis and protein folding /\ Alan Fersht
|
| Publication Statement
|
:
|
New York :: W.H. Freeman,, [1999]
|
|
|
:
|
, [1998]
|
|
|
:
|
, ©1999
|
| Page. NO
|
:
|
xxi, 631 pages :: illustrations ;; 25 cm
|
| ISBN
|
:
|
0716732688
|
|
|
:
|
: 9780716732686
|
| Notes
|
:
|
"First printing 1998"--Title page verso
|
| Bibliographies/Indexes
|
:
|
Includes bibliographical references and index
|
| Contents
|
:
|
The Three-dimensional Structure of Proteins -- Chemical Catalysis -- The Basic Equations of Enzyme Kinetics -- Measurement and Magnitude of Enzymatic Rate Constants -- The pH Dependence of Enzyme Catalysis -- Practical methods for Kinetics and equilibria -- Detection of Intermediates in Enzymatic Reactions -- Stereochemistry of Enzymatic Reactions -- Active-site-directed and Enzyme-activated Irreversible Inhibitors : Affinity Labels and Suicide Inhibitors -- Conformational Change, Allosteric Regulation, Motors, and Work -- Forces Between Molecules and Binding Energies -- Enzyme-substrate Complementarity and the Use of Binding Energy in Catalysis -- Specificity and Editing Mechanisms -- Recombinant DNA Technology -- Protein Engineering -- Case studies of enzyme structure and mechanism -- Protein Stability -- Kinetics of Protein Folding -- Folding Pathways and Energy Landscapes
|
| Abstract
|
:
|
Includes four new chapters which focus on the repercussions of protein engineering for protein folding and catalysis, this new edition is a more general guide to mechanism in protein science
|
| Subject
|
:
|
Enzyme kinetics
|
| Subject
|
:
|
Enzymes
|
| Subject
|
:
|
Protein folding
|
| Subject
|
:
|
Proteins-- Structure
|
| Subject
|
:
|
Enzymes
|
| Subject
|
:
|
Protein Conformation
|
| Subject
|
:
|
Protein Engineering
|
| Subject
|
:
|
Protein Folding
|
| Subject
|
:
|
Enzimas
|
| Subject
|
:
|
Proteínas
|
| Dewey Classification
|
:
|
547/.75
|
| LC Classification
|
:
|
QD431.25.S85F47 1999
|
| NLM classification
|
:
|
QU 55F399s 1999
|
| |