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" Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors "
edited by O.D. Wiestler, U. Schlegel, J. Schramm.
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BL
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| Record Number
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715732
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b537886
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| Main Entry
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edited by O.D. Wiestler, U. Schlegel, J. Schramm.
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| Title & Author
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Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors\ edited by O.D. Wiestler, U. Schlegel, J. Schramm.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1994
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| Series Statement
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Recent results in cancer research, 135.
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(ix, 200 pages 39 illustrations)
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| ISBN
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3642850391
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: 9783642850394
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| Contents
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Contents Molecular Neuro-oncology: Human Neuroblastoma --;Epidermal Growth Factor Receptor Gene and Its Transcripts in Glioblastomas --;Type and Frequency of p53 Mutations in Tumors of the Nervous System and Its Coverings --;Astrocytic Gliomas --;Prognostic Relevance of Transforming Genes --;Oncogene Transfer into the Brain --;The O-2A Lineage --;Clinical Neuro-oncology: The Anti-Hu Syndrome --;Radiosurgery/Stereotactic External Beam Radiotherapy for Malignant Brain Tumors --;Interstitial Implant Radiosurgery of Brain Tumors --;Interstitial Brachytherapy of Malignant Gliomas --;Aggressive Oligodendroglioma --;Chemotherapy of Malignant Gliomas --;Interstitial Chemotherapy with Sustained-Release Polymer Systems for the Treatment of Malignant Gliomas --;Primary Central Nervous System Lymphoma --;Epidermal Growth Factor Receptor Expression in Human Malignant Glioma --;Target Cell Induced T Cell Activation with Bispecific Antibodies.
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| Abstract
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Tumors of the nervous system represent a difficult therapeutic challenge. During recent years, substantial progress has been made in characterizing genetic mechnisms involved in the formation of brain tumors. There is a lot of hope that an understanding of the molecular basis of transformation will eventually lead to specific therapeutic approaches. In this volume, leading authorities in both molecular and clinical neuro-oncology summarize recent developments in their respective fields. The first part of the book will focus on specific molecular genetic defects in neural tumors and their potential clinical significance. Part two gives an update on established and novel treatment regimens for patients with brain tumors. Several contributions will demonstrate that molecular and clinical neuro-oncology are already entangled. With its unique combination of molecular biological and clinical data, this volume provides basic researchers and clinical neuroscientists with a comprehensive update in both disciplines.
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Medicine.
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Nervous system -- Surgery.
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Neurology.
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J Schramm
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O D Wiestler
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U Schlegel
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