| Document Type
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BL
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| Record Number
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719633
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| Doc. No
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b539325
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| Main Entry
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edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg.
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| Title & Author
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Central nervous system diseases : : innovative animal models from lab to clinic\ edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg.
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| Publication Statement
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Totowa, N.J.: Humana Press, ©2000.
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| Series Statement
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Contemporary neuroscience.
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| Page. NO
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(xv, 512 pages) : illustrations
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| ISBN
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0585425299
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: 1592596916
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: 1617371521
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: 9780585425290
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: 9781592596911
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: 9781617371523
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| Contents
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1 --;The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use and Integration of Animal Models --;2 --;Patterns of Cognitive Decline in the Aged Rhesus Monkey --;3 --;Cholinergic Lesions as a Model of Alzheimer's Disease: Effects of Nerve Growth Factor --;4 --;The Immunolesioned Animal as a Model of Transmitter Dysfunction --;5 --;An Intracerebral Tumor Necrosis Factor-? Infusion Model for Inflammation in Alzheimer's Disease --;6 --;The Senescence-Accelerated Mouse as a Possible Animal Model of Senile Dementia --;7 --;Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype and Utility in the Modeling of Alzheimer's Disease --;8 --;Intervention Strategies for Degeneration of Dopamine Neurons in Parkinsonism: Optimizing Behavioral Assessment of Outcome --;9 --;Development of Behavioral Outcome Measures for Preclinical Parkinson's Research --;10 --;Behavioral Assessment in the Unilateral Dopamine-Depleted Marmoset --;11 --;Molecules for Neuroprotection and Regeneration in Animal Models of Parkinson's Disease --;12 --;Antisense Knockdown of Dopamine Receptors --;13 --;Is Trophic Factor Gene Disruption a 'Knockout' Model for Parkinson's Disease? --;14 --;Operant Analysis of Striatal Dysfunction --;15 --;Intrastriatal Injections of Quinolinic Acid as a Model for Developing Neuroprotective Strategies in Huntington's Disease --;16 --;Systemic Administration of 3-Nitropropionic Acid: A New Model of Huntington's Disease in Rat --;17 --;Replicating Huntington Disease's Phenotype in Nonhuman Primates --;18 --;Transgenic Mouse Models of Huntington's Disease --;19 --;Rigid Indentation Models of Traumatic Brain Injury in the Rat --;20 --;Rodent Ischemia Models of Embolism and Ligation of the Middle Cerebral Artery: Clinical Relevance to Treatment Strategies of Stroke --;21 --;A Primate Model of Hypertensive Cerebrovascular Disease --;22 --;Nictotinic Therapeutics for Tourette Syndrome and Other Neuropsychiatric Disorders: From Laboratory to Clinic --;23 --;Neural Grafting for Parkinson's and Huntington's Disease --;24 --;Future Prospects of Gene Therapy for Treating CNS Diseases.
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| Abstract
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Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases.
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| Subject
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Aging -- physiology.
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| Subject
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Alzheimer Disease -- physiopathology.
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| Subject
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Central nervous system -- Diseases -- Animal models.
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| LC Classification
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RC361.E358 2000
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| Added Entry
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Dwaine F Emerich
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Paul R Sanberg
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Reginald L Dean
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