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" New Concepts in Viral Heart Disease Virology, Immunology and Clinical Management "
H P Schultheiß
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BL
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| Record Number
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719926
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b539619
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| Main Entry
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H P Schultheiß
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| Title & Author
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New Concepts in Viral Heart Disease Virology, Immunology and Clinical Management\ H P Schultheiß
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| Edition Statement
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Softcover reprint of the original 1st ed. 1988
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| Publication Statement
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Berlin Springer Berlin, 2013
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| Page. NO
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XI, 504 Seiten in 1 Teil XI, 504 Seiten, 140 schw.-w. Illustrationen, 16 farbige Illustrationen, 58 schw.-w. Tabellen 244 x 170 mm
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| ISBN
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3642736122
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: 9783642736124
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| Contents
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I. Epidemiology and Natural History.- The Etiology, Pathogenesis and Pathophysiology of Dilated Cardiomyopathies.- Virological, Immunological and Clinical Features of Myocarditis and Dilated Cardiomyopathy.- Epidemiology and Pathogenicity of Coxsackieviruses.- Natural History of Acute Viral or Idiopathic Myocarditis: A Clinical and Endomycardial Biopsy Follow-up.- Myocarditis in Patients with Dilated Cardiomyopathy- Correlation with Clinical, Hemodynamic and Biochemical Findings.- Coxsackievirus Cardiomyopathy in Animal Models, Including the Augmenting Effect of Exercise During the Acute Phase.- II. Concepts in Viral Pathogenesis.- Replication, Molecular Biology, and Pathogenesis of Coxsackieviruses.- A Murine Model for Coxsackievirus B3-Induced Acute Myocardial Necrosis for Study of Cellular Receptors as Determinants of Viral Tropism.- Induction of Soluble Mediators During Coxsackievirus B3 Replication In Vitro and In Vivo.- Persistence of Echovirus Type 6 in Cultured Cells.- Detection and Typing of Enteroviruses by Nucleic Acid Probes and Monoclonal Antibodies.- Generation of Enterovirus Group-Specific Antisera Using Bacterially Synthesized Coxsackievirus B3 Proteins.- III. Virus and Immunity.- Myocarditis: A Post-infectious Autoimmune Disease.- Viral Myocarditis: Immunogenetic and Autoimmune Aspects.- Is Coxsackievirus B3-Induced Myocarditis in A/J Mice Mediated by an Autoimmune Response to Cardiac Myosin?.- Virus-Induced Autoimmunity: Cross-Reactivity of Antiviral Antibodies with Self-Components.- Immunopathogenic Mechanisms in Experimental Myocarditis: Evidence for Autoimmunity to the Virus Receptor and Antigenic Mimicry Between the Virus and Cardiocyte.- Coxsackie B3 Myocarditis: Genetic Aspects of Different Immunopathogenetic Mechanisms in BALB/c and DBA/2 Mice. Antigenic Specificity of Heart-Reactive Antibodies in DBA/2 Mice.- Interactions of Group B Coxsackieviruses with Immunocytes.- Early Cellular Infiltrates in Coxsackievirus B3 Murine Myocarditis.- IV. Characterization of Autoimmunological Mechanisms.- Beta-Adrenoceptor Autoantibodies in Idiopathic Dilated Cardiomyopathy.- Antibodies Against the ADP/ATP Carrier Crossreact with the Ca-Channel - Functional and Biochemical Data.- Antibodies and Autoantibodies against ADP/ATP Carrier Enhance Calcium Current in Isolated Ventricular Myocytes.- Antibodies Against the ADP/ATP Carrier Alter Myocardial Function by Disturbing Cellular Energy Metabolism.- The Importance of Humoral and Cellular Immunological Parameters for the Pathogenesis of Viral Myocarditis.- Characterization of T-Lymphocytes Cultured from Human Endomyocardial Biopsies.- V. Diagnostic Criteria.- The Role of Biopsy in the Diagnosis and Follow-up of Myocarditis. A Critical Review.- Impaired Myocardial Ultra-Structure and Cytoskeleton in Cardiomyopathic Human Myocardium.- Immunofluorescence Microscopy in the Diagnosis and Follow-up of Patients Suspected of Having Inflammatory Heart Disease.- of Major Histocompatibility (MHC) Antigens on Myocardial Cells in Patients with Active Myocarditis and Idiopathic Cardiomyopathy.- Evalution of Immunohistological Data for the Diagnosis of Myocarditis.- Enteroviral Heart Disease: Diagnosis by In Situ Hybridization.- Persistence of Enterovirus RNA in Dilated Cardiomyopathy: A Progression from Myocarditis.- Diagnosis of Acute Myocarditis with Radiolabeled Monoclonal Antimyosin Antibody: Immunoscintigraphic Evaluation.- VI. Immuno-Modulating Therapy: Experimental and Clinical Approaches.- Animal Models for Therapeutic Trials of Viral Myocarditis: Effect of Ribavirin and Alpha Interferon on Coxsackievirus B3 and Encephalomyocarditis Virus Myocarditis.- Antiviral Activity of Human Fibroblast Interferon in Coxsackievirus B3-Infected Cultured Human Heart Cells.- Immunosuppressive Therapy in Myocarditis: Acute Viral Versus Chronic Idiopathic Myocarditis.- Immunosuppressive Treatment in Myocarditis.- The Role of Cardiac Transplantation in Patients with Active Myocarditis.- Clinical and Experimental Aspects of Treatment for Viral Myocarditis.- VII. New Aspects of Clinical Management.- Alterations of Receptors and of Agonist Effectiveness in Myocardial Failure.- Positive Inotropic Drugs in the Treatment of Chronic Congestive Heart Failure: A Critical Up-date.- Effect of ACE-Inhibitors on Myocardial Perfusion.- Experimental Evidence for Cardioprotection Afforded by Ramipril, an Inhibitor of Angiotensin Converting Enzyme.- Energetic Consequences of Pharmacological Therapy in Patients with Myocardial Failure.- The Effect of ACE Inhibitors on Energy Metabolism in Chronic Heart Failure - Enzymatic Studies of Myocardial Biopsies.
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| LC Classification
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RC685.V57H673 2013
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H P Schultheiß
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