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" Molecular Cancer Therapeutics: "
George C Prendergast
Document Type
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BL
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Record Number
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723044
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Doc. No
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b542758
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Main Entry
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George C Prendergast
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Title & Author
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Molecular Cancer Therapeutics: : Strategies for Drug Discovery and Developmen.\ George C Prendergast
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Publication Statement
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John Wiley & Sons, 2004
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Page. NO
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351 s
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ISBN
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0471432024
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: 9780471432029
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Contents
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Preface.Contributors.Chapter 1. Introduction (G. Prendergast).Chapter 2. Molecular Cancer Therapeutics: Will the Promise Be Fulfilled? (B. Teicher).Chapter 3. Cancer Genetics and Drug Target Selection (G. Zhang & W. Kaelin).Chapter 4. RNA Interference in Mammals: Journey to the Center of Human Disease (P. Paddison & G. Hannon).Chapter 5. Applications and Issues for Tissue Arrays in Target and Drug Discovery (E. Jonasch, K. Do, C. Logothetis, & T. McDonnell).Chapter 6. Protein Transduction Strategies for Target and Mechanism Validation (S. Ezhevsky & S. Dowdy).Chapter 7. Drug Screening: Assay Development Issues (S. Carroll, J. Inglese, S. Mao, & D. Olson).Chapter 8. Gene Microarray Technologies for Cancer Drug Discovery and Development (R. te Poele, P. Clarke, & P. Workman).Chapter 9. Transgenic Mouse Models of Cancer (T. Bowen & A. Wynshaw-Boris).Chapter 10. Transgenic versus Xenograft Mouse Models of Cancer: Utility and Issues (M. Liu, W. Bishop, Y. Wang, & P. Kirschmeier).Chapter 11. Pharmacodynamic Assays in Cancer Drug Discovery: From Preclinical Validation to Clinical Trial Monitoring (R. Lobell, N. Kohl, & L. Sepp-Lorenzino).Chapter 12. Pharmacokinetic and Toxicology Issues in Cancer Drug Discovery and Development (P. Benfield & B. Car).Chapter 13. Clinical Development Issues (S. Averbuch, M. Wolf, B. El-Rayes, & P. LoRusso).Chapter 14. Intellectual Property and Commercialization Issues in Drug Discovery (L. Malseed).Index.
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LC Classification
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RC271.C5G467 2004
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Added Entry
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George C Prendergast
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