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" Medical and Nutritional Complications of Alcoholism Mechanisms and Management. "
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BL
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| Record Number
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723260
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b542974
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| Title & Author
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Medical and Nutritional Complications of Alcoholism Mechanisms and Management.
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| Publication Statement
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Springer Verlag, 2013
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| ISBN
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1461533201
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: 9781461533207
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| Contents
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1. Metabolism of Ethanol.- 1.1. Pathways of Ethanol Oxidation.- 1.2. Alteration in the Metabolism of Ethanol after Chronic Ethanol Consumption.- 1.3. Effects of Liver Disease, Blood Flow, Circadian Rhythm, Gender, and Other Factors on Hepatic Alcohol Metabolism.- 1.4. Effects of Other Drugs on Ethanol Metabolism.- 1.5. Ethnic and Genetic Factors in Ethanol Metabolism.- 1.6. Extrahepatic Ethanol Metabolism.- 1.7. Summary.- References.- 2. Acetaldehyde and Acetate.- 2.1. Pathways of Acetaldehyde and Acetate Metabolism.- 2.2. Effect of Chronic Ethanol Consumption on Acetaldehyde and Acetate Metabolism.- 2.3. Effect of Liver Injury on Acetaldehyde Metabolism.- 2.4. Effects Attributable to Acetaldehyde and Acetate after Acute and Chronic Ethanol Consumption.- 2.5. Summary.- References.- 3. Alcohol, Hormones, and Metabolism.- 3.1. Hypothalamic-Pituitary-Thyroidal Axis.- 3.2. Parathormone and Calcitonin.- 3.3. Adrenocortical Function: Glucocorticoid Secretion.- 3.4. Adrenocortical Function: Mineralocorticoid Secretion.- 3.5. Adrenal Medullary Function.- 3.6. Growth Hormone.- 3.7. Antidiuretic Hormone and Oxytocin.- 3.8. Pancreatic and Gastrointestinal Hormones.- 3.9. Alteration of Carbohydrate Metabolism by Alcohol.- 3.10. Effects of Ethanol on Ketone Metabolism.- 3.11. Alcoholic Ketoacidosis.- 3.12. Hyperlactacidemia and Lactic Acidosis.- 3.13. Alcoholic Hyperuricemia and Its Relationship to Gouty Attacks.- References.- 4. Ethanol and Lipid Disorders, Including Fatty Liver, Hyperlipemia, and Atherosclerosis.- 4.1. Interaction of the Metabolism of Ethanol and Lipids.- 4.2. Pathogenesis of the Alcoholic Fatty Liver.- 4.3. Agents and Procedures that Prevent the Alcoholic Fatty Liver.- 4.4. Effects of Ethanol on Blood Lipids: Characteristics and Pathogenesis of Alcoholic Hyperlipemia.- 4.5. Ethanol, Atherosclerosis, and High-Density Lipoproteins.- 4.6. Interaction of Ethanol with Vascular Prostacyclin Production.- 4.7. Summary.- References.- 5. Effects of Ethanol on Amino Acid and Protein Metabolism.- 5.1. Effects of Ethanol on Nitrogen Balance and Body Protein Composition.- 5.2. Effects of Ethanol on Amino Acids.- 5.3. Effects of Ethanol on Hepatic Protein Synthesis.- 5.4. Effects of Ethanol on Hepatic Protein Secretion.- 5.5. Effects of Ethanol on Hepatic Protein Catabolism.- 5.6. Hepatic Accumulation of Protein after Chronic Ethanol Feeding.- 5.7. Dietary Requirements for Protein in the Alcoholic.- 5.8. Summary.- References.- 6. Interaction of Ethanol with Other Drugs.- 6.1. Interaction with Drug Absorption.- 6.2. Interaction with Plasma Protein Binding.- 6.3. Interaction with Hepatic Blood Flow.- 6.4. Interaction with Hepatic Cell Uptake.- 6.5. Interaction with Hepatic Metabolism.- 6.6. Pharmacological Interactions.- 6.7. Summary and Therapeutic Guidelines.- References.- 7. Alcohol and the Liver.- 7.1. Epidemiology of Alcoholic Liver Disease.- 7.2. Pathology and Symptomatology of the Various Stages of Alcoholic Liver Injury.- 7.3. Pathogenesis of Alcoholic Liver Injury.- 7.4. Diagnosis of Alcoholic Liver Injury.- 7.5. Prognosis and Treatment of Alcholic Liver Injury.- References.- 8. Alcohol and the Hematologic System.- 8.1. Red Cells.- 8.2. Platelets.- 8.3. Granulocytes.- 8.4. Monocytes and Macrophages.- 8.5. Lymphocytes.- 8.6. Other Factors Favoring Infection.- 8.7. Summary.- References.- 9. Immunologic Reactions in Alcoholic Liver Disease.- 9.1. Morphological Considerations.- 9.2. Genetic Factors.- 9.3. Immunoglobulins, Antibodies, and Immune Complexes.- 9.4. Hepatitis B Virus (HBV).- 9.5. Hepatitis C Virus (HCV).- 9.6. Serum Factors and Cytokine Activity.- 9.7. Cell-Mediated Alterations.- 9.8. Abnormal Antigen Expression on Liver Cells.- 9.9. Alcohol and Alteration of the Immune Response in Alcoholics without ALD.- 9.10. Summary.- References.- 10. Alcohol and the Digestive Tract.- 10.1. Introduction.- 10.2. Oropharynx and Salivary Glands.- 10.3. Esophagus.- 10.4. Stomach.- 10.5. Effect of Alcohol on the Small Intestine.- 10.6. Effects of Alcohol on the Colon.- References.- 11. Ethanol and the Pancreas.- 11.1. Introduction.- 11.2. Epidemiology of Alcoholic Pancreatitis.- 11.3. The Pathology of Alcoholic Pancreatitis.- 11.4. Pathogenesis of Alcoholic Pancreatitis.- 11.5. Nutrition.- 11.6. Summary: Pathogenesis of Alcoholic Pancreatitis.- 11.7. Clinical Aspects of Alcoholic Pancreatitis.- References.- 12. Cardiovascular Effects of Ethanol.- 12.1. Acute Hemodynamic Effects of Ethanol.- 12.2. The Acute Metabolic Effects of Ethanol on the Heart.- 12.3. Changes in Regional Blood Flow Caused by Ethanol.- 12.4. Alcoholic Cardiomyopathy.- 12.5. Effects of Prolonged Alcohol Exposure in Experimental Animals.- 12.6. Holiday Heart.- 12.7. Hypertension.- 12.8. Stroke.- 12.9. Relationship of Alcohol Use to Coronary Artery Disease.- References.- 13. Effects of Alcohol Abuse on Skeletal Muscle.- 13.1. Introduction.- 13.2. Clinicopathological Classification.- 13.3. Clinicopathological Features of Acute Myopathy.- 13.4. Clinicopathological Features of Chronic Myopathy.- 13.5. Prevalence of Alcoholic Myopathy.- 13.6. Pathogenesis of Alcoholic Myopathy.- 13.7. Treatment and Prognosis.- References.- 14. The Effects of Alcohol on the Nervous System: Clinical Features, Pathogenesis, and Treatment.- 14.1. Alcoholic Intoxication.- 14.2. Alcohol Withdrawal Syndrome.- 14.3. Nutritional Diseases of the Nervous System Secondary to Alcoholism.- 14.4. Alcoholic Cerebellar Degeneration.- 14.5. Alcoholic Neuropathy.- 14.6. Alcohol (Tobacco-Alcohol) Amblyopia.- 14.7. Pellagra.- 14.8. Central Pontine Myelinolysis.- 14.9. Marchiafava-Bignami Disease (Primary Degeneration of the Corpus Callosum).- 14.10. Alcoholic Dementia.- 14.11. Alcoholic Cerebral Atrophy.- 14.12. Hepatic Encephalopathy.- References.- 15. Alcohol Abuse: Carcinogenic Effects and Fetal Alcohol Syndrome: Description, Diagnosis, and Prevention.- 15.1. Alcohol and Cancer.- 15.2. Ethanol as a Cocarcinogen.- 15.3. Animal Studies.- 15.4. Biochemical Bases for Ethanol's Activity as a Cocarcinogen.- 15.5. Hepatitis B Virus and Hepatocellular Carcinoma.- 15.6. Dietary Deficiencies and Alcohol Abuse.- 15.7. Fetal Alcohol Syndrome: Description, Diagnosis, and Prevention.- References.- 16. Alcohol and the Kidney.- 16.1. Changes in Renal Anatomy.- 16.2. Renal Hemodynamics.- 16.3. Renal Sodium Handling.- 16.4. Hypophosphatemia in the Alcoholic.- 16.5. Effects on Renal Calcium Handling.- 16.6. Effects on Renal Magnesium Handling.- 16.7. Renal Water Handling.- 16.8. Chronic Effects of Ethanol.- 16.9. Hyponatremia in Alcoholics without Cirrhosis.- 16.10. Acid-Base Disturbances Induced by Alcohol.- 16.11. Acidosis Caused by Toxin Ingestion.- 16.12. Abnormalities of Acid-Base Status in Liver Disease.- 16.13. Renal Tubular Acidosis.- 16.14. Effects on the Renin-Aldosterone System and Adrenocortical Function.- 16.15. Effects on Blood Pressure.- 16.16. Summary.- References.- 17. Nutrition: Medical Problems of Alcoholism.- 17.1. General Nutritional Status in the Alcoholic Including Disorders of Minerals and Vitamins.- 17.2. Nutritive Aspects of Alcohol and Alcoholic Beverages.- 17.3. Nutritional Status of Alcoholics.- 17.4. Water-Soluble Vitamins.- 17.5. Fat-Soluble Vitamins.- 17.6. Minerals and Electrolytes.- 17.7. Nutritional Therapy.- References.- 18. Biological Markers of Alcoholism.- 18.1. Utility of a Biological Marker of Alcoholism.- 18.2. Currently Available Markers.- 18.3. Special Laboratory Markers.- 18.4. Biological Markers of a Predisposition to Alcoholism.- 18.5. Combination of Markers.- 18.6. Summary.- References.
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QP801.A3M435 2013
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