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" Atherosclerosis VI Proceedings of the Sixth International Symposium "
F G Schettler
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BL
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724479
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b544198
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F G Schettler
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Atherosclerosis VI Proceedings of the Sixth International Symposium\ F G Schettler
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Berlin Springer Berlin, 2013
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XXVIII, 982 Seiten in 1 Teil 264 Figuren, 214 Tabellen XXVIII, 982 Seiten ., 214 schw.-w. Tabellen 244 x 170 mm
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3642818196
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: 9783642818196
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| Contents
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1 Clinical Aspects of Atherosclerosis.- Atherosclerosis. The Major Problem in Man.- Clinical Aspects of Atherosclerosis-Recent Advances in Diagnosis and Evaluation of Coronary Heart Disease.- Recent Advances in Diagnosis and Evaluation. Peripheral Artery Disease.- Atherosclerosis. Recent Advances in Diagnosis and Evaluation - Cerebrovascular Disease.- Clinical Aspects of Atherosclerosis. Role of Coronary Artery Spasm.- Conservative Treatment of Coronary Heart Disease.- Conservative Treatment of Peripheral Artery Disease.- 1.1 Atherosclerosis in Childhood.- An Introduction to Atherosclerosis in Children.- Clinical and Anatomic Correlates of Cardiovascular Disease in Children from the Bogalusa Heart Study.- Dietary Prevention of Atherosclerosis in Childhood.- Early Indicators for the Risk of Atherogenesis. A. Field Test of a New Methodology on German and Japanese Kindergarten Children in Dusseldorf.- Morphologic Changes in Coronary Arteries of Children in Different Geographic Locations.- Structure and Ultrastructure of the Coronary Artery Intima in Children and Young Adults up to age 29.- The Natural History of Aortic Atherosclerosis in Children, Adolescents and Young Adults.- Immunohistology of Aortic Fatty Streaks in Children and Adults.- 1.2 Diseases of Lipid Metabolism.- Heterogeneity of Genetic Transmission of Familial Hypercholesterolemia F. H. from Direct Parents in 20 Families of Homozygotes Type IIa.- The Impact of Analbuminemia on Lipid Transport and Lipoproteins.- Familial Hypertriglyceridemia: Incidence, Genetics and Possible Defect in Cellular Metabolism.- Phytosterolemia.- Familial Chylomicronaemia due to a Circulating Inhibitor of Lipoprotein Lipase.- 1.3 Animal Models of Atherosclerosis.- Experimental Nonhuman Primate Atherosclerosis.- Platelets and Atherogenesis in Normal and von Willebrand Disease Pigs.- Lipid Accumulation in the Rabbit Aortic Wall in Response to Injury.- WHHL Rabbit, a Heritable Animal Model of Familial Hypercholesterolemia.- Hypertensive Rat Models of Atherosclerosis.- Seeking for More Similarity Between Animal Models and Human Atherosclerosis.- Lipoproteins, Blood Cells and Endothelial Integrity in Atherosclerosis: What Role for Eicosanoids?.- 1.4 Measurement and Identification of Atherosclerosis.- Chairman's Comments on the Discussion at the Workshop on Measurement of Atherosclerosis.- Measurement of Regression in Atherosclerosis.- Measurement of Monotypism in Atherosclerosis.- Measurement of Human Atherosclerosis.- Identification of the Gelatinous Lesion.- Quantitation of Certain Qualitative Differences in the Atherosclerotic Process.- 1.5 Regression.- Chairman's Introduction to Workshop on Regression.- Preliminary Report on Coronary Lesions and Serum Lipids Before and after 2 Years Dietary Intervention in 22 Patients.- Measurement of Atherosclerosis by Arteriography and Microdensitometry: Model and Clinical Investigations.- Role of Macrophages in Regression of Swine Atherosclerosis.- Potential for Atherosclerosis Regression in Perspective.- The Biochemical Basis for Anatomical Regression of Atherosclerosis.- The Endothelial Changes During Regression of Atherosclerotic Lesions in Animal Models.- 1.6 Diet.- Diet and Carcinogenesis.- Effects of Dietary Cholesterol and Saturated-Fat on the Appearance of HDLc in Peripheral and Cardiac Lymph.- Dietary Fibres for Prevention of CVD.- Dietary Cholesterol and Plasma Lipoproteins.- Experience with Soybean Protein Diets in Treating Hypercholesterolemias.- Dietary Fatty Acids as Prostaglandin Precursors.- Effects of Dietary Treatment on Lipoplitic Activities and Lipids and Apolipoproteins in Patients with Uremia.- 1.7 Exercise.- 6th International Symposium on Atherosclerosis. Introduction.- Therapeutical Effects of Endurance Training in Primary Hyperlipoproteinemia.- Atherosclerotic Disease in Non-Human Primates: Its Prevention and Regression by Moderate Conditioning Exercise.- The Effect of Different Types of Exercise on Serum Lipids.- Physical Exercise as Protection Against Heart Attack.- Exercise and Fibrinolysis.- Regulation of Serum Triglycerides in Trained Subjects.- Exercise and Arachidonic Metabolites: Effects of Adrenergic Beta Blockade.- Effect of Physical Training on Blood Pressure and Serum Lipoproteins in Middle-Aged Men with Borderline Hypertension.- 1.8 Drug Therapy of Hyperlipoproteinemias.- The Treatment of Hyperlipaemia by Gemfibrozil: a Comparison with Clofibrate.- Lipid-Lowering Agents and Apolipoproteins B, A-I, and A-II-a Longterm Study.- Compliance and Cholesterol-Lowering in Clinical Trials: Efficacy of Diet.- Long-Term Treatment of Hypercholesterolaemia with Guar Gum: Comparison with Probucol.- 1.9 Flow Restituting, Nonsurgical Intervention in Cardiovascular Disease.- Gross Endothelial Layer Blistering and Vascular Injury.- Haemodynamic Influences on Platelets in Haemostasis and Thrombosis.- Effect of Stresses on the Uptake of Material by the Arterial Wall.- Percutaneous Transluminal Angioplasty in the Treatment of Peripheral Vascular Disease.- Metabolic and Haemodynamic Effects of Plasma-Exchange in Familial Hypercholesterolemia.- 2 Arterial Wall and Plasma Components.- Role of Endothelial Dysfunction in Vivo in Smooth Muscle Proliferation.- Derivation and Progression of Atherosclerotic Plaques.- Hemodynamics as a Factor in Lesion Lacalization.- Role of Connective Tissue in the Arterio-Atherosclerotic Process. Interest of a Cell-Matrix Directed Pharmacology.- Arterial Wall Cells and Mitogens.- 2.1 Biology of Arterial Wall Cells.- The Microcarrier Co-Culture System: Interactions Between Endothelial and Smooth Muscle Cells in Vitro.- Intermediate Filaments of the Vascular Wall.- A Putative Mechanism for the Conversion of Aortic Smooth Muscle Cells into Foam Cells that Bypasses the Autoregulatory LDL Receptor-Mediated Process.- Structure and Function of Arterial Smooth Muscle Cells.- Alterde Growth Stimulation and LDL-Degradation in Human Arterial Smooth Muscle Cells ASMC and Fibroblasts F by Low Molecular Weight Serum Factors from Typre II Diabetics.- 2.2 Growth Factors and the Arterial Wall.- Platelet-Derived Growh Factors: Properties and Biologic Activities.- Preparation and Characterisation of Platelet-Derived Growth Factor.- Effects of PDGF and Endothelial Cell Products on Cellur Lipid and Lipoprotein Metabolism in Human Fibroblasts.- 2.3 HMG-Co A Reductase and Cell Metabolism.- Site of Action of LCAT in Plasma.- The Isolation and Partial Characterisation of two Lipid Transfer Proteins LTP-I and LTP-II, Each of which Facilitates the Transfer of Esterified Cholesterol, Triglyceride and Phospholipid Between Plasma Lipoproteins.- Besides Blockage of the Synthesis of HMG - Co A Reductase, Cycloheximide also Inhibits its Degradation.- Intestinal HMG-CoA Reductase: Regulation and Function.- 2.4 Phagocytosis in the Lesion.- Fluid-Phase Pinocytosis in Arterial Smooth Muscle Cells.- Interaction of Platelets, Macrophages and Lipoproteins in Relation to Atherogenesis.- Role of Macrophage Foam Cells in Arterial Lesions.- Chemotactic Responses of Monocyte-Macrophages.
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A Possible Mechanism for Their Migration into Atherosclerotic Lesions.- Macrophages in Coronary Artery and Aortic Intima and in Atherosclerotic Lesions of Children and Young Adults up to Age 29.- 3 Lipoproteins-An Overview.- Structure-Function Relationships in the Plasma Lipoproteins.- Metabolism of Triglyceride-Rich Lipoproteins.- Apolipoprotein E and Cholesterol Metabolism.- Selective Removal of Plasma Low-Density Lipoproteins by Combined Extracorporeal Plasma Separation-Immunoadsorption.- 3.1 Structural and Metabolic Aspects of Lipoproteins.- Apolipoprotein Mutants and Apolipoprotein Disorders.- Determination of Plasma Apolipoprotein Profiles.- The Plasma Cholesterol: Cholesterol-Ester Cycle.- Pathogenesis of Secondary Hyperlipoproteinemia.- Surface Organization of the Apolipoproteins of Plasma High Density Lipoproteins and Pelevance to Functions.- Receptor Interactions of Human Apolipoprotein.- Effects of Hormones on Plasma Lipoprotein Concentrations.- 3.2 Lipoprotein Receptors.- Monoclonal Antibody as a Probe for Structural and Functional Studies of the LDL Receptor.- The Role of Receptors in Apolipoprotein B Metabolism.- Factors Influencing Receptor-Mediated Low Density Lipoprotein Catabolism.- Rat and Human Lipoprotein Utilization by Cultured Rat Ovary Granulosa Cells.- 3.3 Regulation of Lipoprotein Synthesis and Secretion.- Contribution of Apoprotein B Production Rate in the Regulation of Lipoprotein Levels in Man.- Measurements of C Apoprotein Kinetics in Man.- Regulation of Rat Liver Apolipoprotein E mRNA and Cloning of its cDNA.- Effect of LP-X on Hepatic Cholesterol Synthesis.- 3.4 Apolipoproteins.- Apolipoprotein Research: A Multidisciplinary Task.- Significance of Apolipoproteins for the Biochemical Profile of Atherosclerosis.- Regulation of Lipoprotein Gene Expression.- Apolipoprotein AIV Metabolism in Man.- Mechanism of Action of Lipoprotein Lipase: Role of Apolipoprotein C-II.- Human Apolipoprotein Mutants.- 3.5 Lipolytic Enzymes.- Use of Specific Antibodies in the Study of the Function of Lipoprotein Lipase.- The Role of Hepatic Triglyceride Lipase in Primates.- Function of Hepatic Endothelial Lipase in Lipoprotein Metabolism.- Genetic Regulation of Lipoprotein Lipase.- Lipoprotein Lipase: Apolipoprotein C-II Interactions Studied by Fluorescence and Monoclonal Antibodies.- 4 Thrombosis.- Arachidonic Acid Metabolism in Human Platelets.- Factors Influencing the Growth, Stability and Fate of Arterial Thrombi.- Biosynthesis and Some Biological Properties of Prostaglandins and Leukotrienes.- Interactions Between Lipoproteins and PGI2 under Physiologic and Pathophysiologic Conditions.- 4.1 Platelet Aggregation and Phospholipid Metabolism.- Effects of Platelet-Derived Growth Factor on the Metabolism of Glycerolipids and Arachidonic Acid in Cultured Cells.- The Phosphatidylinositol Response and the Activation of Platelets.- Platelet Phospholipid Fatty Acids and Platelet Aggregation.- Regulatory Function of the Cellular Thiol-Disulfide Status in the Metabolic Control of Human Blood Platelet Aggregation.- 4.2 Prostanoids..- The Formation of Eicosanoids During Inflammation.- Prostaglandins, Cyclic Nucleotides and Atherosclerosis.- Prostacyclin Formation, Plasma Factor, Platelet Sensitivity and Prostacyclin Degradation in Coronary Heart Disease.- Vascular Resistance and Platelet Function on Cardiovascular Drugs and Diets Affecting Prostanoid Formation.- 5 Epidemiology and Prevention.- Coronary Heart Disease-Geographical Differences and Time Trends.- Coronary Disease Rist Factors: A Population View.- Pediatric Precursors of Atherosclerosis.- Intervention on Single Risk Factors: Hyperlipoproteinemia.- Intervention of Single Risk Factor: Hypertension.- Intervention of Single Risk Factors of Atherosclerosis: Thrombosis.- Intervention on Smoking: An Individual and Collective Challenge.- Multiple Risk Factor Intervention Trials.- Pharmacological Approach to the Prevention of Atherosclerosis.- 5.1 Epidemiology.- Role of Lipid Profiles in Assessing Atherogenesis.- Plasma Lipids and Lipoprotein Cholesterol Distributions and Correlates of HDL Cholesterol in Selected US and USSR Subpopulations US-USSR Steering Committee for Cardiovascular Area I: Pathogenesis of Atherosclerosis.- The Belgian Heart Disease Prevention Project: Six Years Coronary Risk Factors Evolution.- Peculiarities of Coronary Heart Disease in the French Population.- The Fate of the Patient with Opad Detected at an Early Stage.- Population Attributable Events-Implications for Prevention.- Risk Factors in Insulin Dependent Diabetics.- Contribution to the Discussion.- Cardiovascular Epidemiology and Preventive Community Programmes in Austria.- 5.2 Hypocholesterolemia- A Risk Factor?.- Clinical Associations of Hypocholesterolaemia.- On a Possible Inverse Relationship Between Plasma Cholesterol and the Risk of Cancer. The Framingham Study.- Cholesterol and Steroid Hormone Metabolism in Abetalipoproteinemia.- Associations Between Plasma Cholesterol, Cell Membrane Composition and Fluidity, and Retinoid Concentrations in a Normal Male Population.- The Prognostic Significance of Hypocholesterolemia in Hospitalized Patients.- The Association of Low Serum Cholesterol Level to the Risk of Cancer. Significance with Respect to Dietary Modification for Coronary Heart Disease Prevention.- Serum Cholesterol and Cancer Mortality in White Males: Social Class Effects, Evans County Twenty Year Foliow-Up Study.- 5.3 Smoking and Atherosclerosis.- Carbon Monoxide and Atherosclerosis.- The Influence of Smoking on Plasmalipoproteins.- Smoking and Atherosclerotic Disease. The Oslo Study.- Epidemiology of Cardiovascular Disease in Different Countries in Relation to Smoking.- Smoking and Atherosclerosis: Risk Factor Reduction.- Nicotine and Atherosclerosis.- Smoking: A Paediatric Disease.- Smoking and Lipid Metabolism.- The Influence of Smoking on Systolic and Diastolic Blood Pressure.- 5.4 Serum Lipid Lowering in Secondary Prevention.- Current Japanese Situations on Secondary Prevention and Lipid Lowering Drugs.- Serum Lipid Lowering ind Secondary Prevention: A Review.- A Controlled Trial of Substantial Reduction of Plasma Lipids in Symptomatic Atherosclerosis: An Angiographic Study.- Program on the Surgical Control of the Hyperlipidemias Posch. A Secondary Intervention Trial-4-Year Lipid Results.- Platelet-Vessel Wall Interactions in Human and Experimental Hypercholesterolemia.- Secondary Prevention of Ischaemic Heart Disease by the Combined Treatment with Clofibrate and Nicotinic Acid.- 6 Risks of Obesity.- Diabetes Mellitus and Obesity.- Hypertension in Obesity.- Surgical Risks in Obese Patients.- Obesity and Lipoprotein Metabolism.- Another Look at Body Weight, Health and Longevity.- 6.1 Addendum.- Status of a Computerized, Angiographic Regression Trial CLAS.
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RC692.F473 2013
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A J R Habenicht
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A M Gotto
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F G Schettler
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G Middelhoff
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K R Jurutka
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