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" Clinical cellular immunology : "
edited by Albert A. Luderer and Howard H. Weetall.
Document Type
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BL
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Record Number
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725897
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Doc. No
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b545620
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Main Entry
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edited by Albert A. Luderer and Howard H. Weetall.
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Title & Author
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Clinical cellular immunology : : molecular and therapeutic reviews\ edited by Albert A. Luderer and Howard H. Weetall.
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Publication Statement
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Clifton, N.J.: Humana Press, ©1982.
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Series Statement
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Contemporary immunology.
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Page. NO
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(xviii, 391 pages) : illustrations.
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ISBN
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1461258022
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: 1461258049
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: 9781461258025
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: 9781461258049
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Contents
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1 The T Cell Antigen Receptor: Structural and Functional Considerations --;1. Overview --;2. Functional and Physical Analysis of T Cell Antigen-Specific Receptors --;3. Serological and Biochemical Analysis of T Cell Antigen-Specific Receptors --;4. Physiologic Constraints in the Recognition Function of the T Cell Antigen Receptor --;5. Cytotoxic T Cell Ligand-Binding Sites are Critically Affected by Recognition Structures on Other Cells --;6. Summary --;References --;2 Regulation of the Immune Response --;1. Introduction --;2. Ir Genes in Guinea Pigs --;3. The Ir-1 Gene --;4. Genetic Control of Immune Responsiveness to Staphylococcal Nuclease --;5. Ia Antigens --;6. Complementing Ir Genes --;7. Immunosuppressor Genes --;8. Genetic Control of Cellular Immune Responses --;9. Human Immune-Response Genes --;10. An Hypothesis to Explain the Interrelationship Among Ir Genes, Ia Antigens, and MLR-Stimulating Determinants --;11. Conclusions --;References --;3 Immunosuppressive Agents: A Conceptual Overview of Their Action on Inductive and Regulatory Pathways --;1. Introduction --;2. Inductive and Regulatory Aspects of Immune Responses: Current Concepts --;3. Classes and Subclasses of Lymphocytes and Their Functions --;4. Antibody Responses to Thymus-Independent and Thymus-Dependent Antigens --;5. Inductive and Regulatory Functions: Antigens, Cells, Cognitive and Regulating Molecules, and Networks --;6. A Closer Look at Induction and Regulation of Cell-Mediated Immunity --;Acknowledgments --;References --;4 Immunosuppressive Agents --;Their Action on Inductive and Regulatory Pathways: The Differential Effects of Agents Used Clinically or Experimentally in the Treatment of Cancer --;1. Variables that Determine the Effect of Cancer Therapeutic Agents on Antibody Production --;2. Diversity of Effects of Immunosuppressive Drugs on CMI --;3. Alkylating Agents Exert Selective Action Against Cells in the Suppressor Pathway --;4. A Closer Look at Agents That Are More Suppressive Before Immunization --;5. The Many Faces and Interfaces of Cyclophosphamide Action --;Acknowledgments --;References --;5 The Immunobiology of Human Non-Hodgkin's Lymphomas --;1. Introduction --;2. Classification Schema --;3. Functional Studies --;4. The Ontogeny of Lymphocytes --;5. Overview of Immunoregulation --;6. Lymphocyte Identification --;7. New Directions --;Acknowledgments --;References --;6 Cell-Mediated Immunity in Autoimmune Disease --;1. Introduction --;2. Self-Recognition and Tolerance --;3. Induction of Autoimmunity --;4. Pathogenic Mechanisms in Autoimmune Disease --;5. Cell-Mediated Immunity in Autoimmune Diseases of Animals --;6. Cell-Mediated Immunity in Autoimmune Disease of Humans --;7. Summary --;References --;7 Cell-Mediated Immunity in Tumor Rejection --;1. Immune Surveillance --;A Theory Under Scrutiny --;2. Tumor Antigens --;3. Effector Mechanisms in Cell-Mediated Immunity --;4. Effector Molecules --;5. Depression of Immunity by Tumors: Suppressor Cells and Factors --;6. Immunotherapy --;7. Conclusions --;References --;8 Transfer Factor and Other Factors in Leukocyte Dialyzates That Affect Cell-Mediated Immunity --;1. Introduction --;2. The Transfer Phenomenon --;3. Clinical Use of Leukocyte Dialyzates or Transfer-Factor Preparations --;4. Biochemical Characterization --;5. Experimental Considerations --;6. Implications for Immunotherapy --;References --;9 Hybridization of Lymphocytes: Techniques and Applications --;1. Introduction --;2. B Cell Hybrids --;3. T Cell Hybrids --;4. Applications and Future Perspectives --;Notes Added in Proof --;Acknowledgment --;References --;10 Immunologic Tests for Diagnosis and Monitoring of Defects in Cell-Mediated Immunity --;1. Introduction --;2. Anatomy of the Immune System --;3. In Vivo Manifestations of Cell-Mediated Immunity --;4. In Vitro Tests of Cell-Mediated Immunity --;5. Clinical Immunodeficiencies --;6. Conclusion --;Acknowledgments --;References.
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Abstract
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This volume offers a coherent survey of both the fundamentals of cellular immunology and its emerging, central role in major areas of clinical medicine. This book should be of interest to immunologists, biochemists, cancer chemotherapists, clinical oncologists and immunopathologists.
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Subject
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Cellular immunity.
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Subject
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Immunologic diseases.
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Subject
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Molecular immunology.
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LC Classification
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RC582.E358 1982
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Added Entry
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Albert A Luderer
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Howard H Weetall
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