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" Genetic Models of Immune and Inflammatory Diseases "
edited by Abul K. Abbas, Richard A. Flavell.
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BL
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| Record Number
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726482
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b546214
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| Main Entry
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edited by Abul K. Abbas, Richard A. Flavell.
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| Title & Author
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Genetic Models of Immune and Inflammatory Diseases\ edited by Abul K. Abbas, Richard A. Flavell.
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| Publication Statement
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New York, NY: Springer New York, 1996
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| Series Statement
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Serono Symposia USA.
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| Page. NO
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(xvi, 177 pages 20 illustrations)
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| ISBN
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1461223768
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: 9781461223764
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| Contents
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I. Autoimmunity --;1. Intensification of Diabetes in B7-1 Transgenic Mice --;2. A Transgenic Window on Self-Reactive T Lymphocytes --;3. Induction and Breaking of Peripheral Tolerance --;4. T-Cell Development and Tolerance in Virus-Specific Transgenic Models --;5. Inflammatory Disease in HLA-B27 Transgenic Rats --;II. Autoimmunity, Infections --;6. The Role of CD40 Ligand in Regulation of Immune Response --;7. Adventures in Antigen Presentation --;8. The Effect of MHC Encoding Transgenes on IDDM in NOD Mice --;9. The Immunology of Leishmania Major Infection in Mice --;III. Cytokines, Co-Stimulators, Tumor Immunity --;10. The Regulatory Functions of Co-Stimulators Revealed in Transgenic Mice --;11. B7-Deficient Mice Reveal an Alternative Functional CTLA-4 Counterreceptor --;12. Cytokine Transgenic Mice and Autoimmunity --;13. Gaining Insights into the Ontogeny and Activation of T Cells Through the Use of Gene-Targeted Mutant Mice --;14. B7-Mediated Co-Stimulation of T Cells: CTLA-4 Can Deliver Inhibitory Signals --;IV. Cytokine Deletions --;15. Lymphoid Organogenesis and Inflammation Are Mediated by Lymphotoxin --;16. The Role of Interferon-? in the Development of Type I Diabetes --;17. Cytokine-Deficient Mouse Mutants --;Author Index.
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| Abstract
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Immunomodulatory agents have been expressed in defined tissues or throughout the body, providing tools for studying the functional consequences of dysregulated expression of biologi- cal response modifiers.
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| Subject
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Human genetics.
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Immunology.
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Medicine.
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| LC Classification
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QR188.3E358 1996
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| Added Entry
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Abul K Abbas
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R A Flavell
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