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" Human Tumour Xenografts in Anticancer Drug Development "
edited by Benjamin Winograd, Michael Peckham, Herbert Michael Pinedo.
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BL
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| Record Number
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726862
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b546594
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| Main Entry
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edited by Benjamin Winograd, Michael Peckham, Herbert Michael Pinedo.
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| Title & Author
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Human Tumour Xenografts in Anticancer Drug Development\ edited by Benjamin Winograd, Michael Peckham, Herbert Michael Pinedo.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1988
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| Series Statement
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ESO Monographs, European School of Oncology.
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| ISBN
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3642732526
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: 3642732542
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: 9783642732522
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: 9783642732546
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| Contents
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I. Biological Behaviour of Human Tumours Transplanted in Mice and the Evaluation of Therapeutic Response --;The Therapeutic Response of a Variety of Human Tumour Xenografts --;Biology of Human Ovarian Cancer Xenografts --;Representativity of Xenografts for Clinical Cancer. Tumor and Host Characteristics as Variables of Tumor Take Rate --;II. Prediction of Tumour Response for the Individual Patient by the Human Tumour Xenograft --;Comparison of Tumor Response in Nude Mice and in Patients --;III. Prediction of Antitumour Activity per Tumour Type by the Human Tumour Xenograft --;Conventional Agents in Human Ovarian Cancer Xenografts --;Activity of Conventional Drugs in Head and Neck Cancer Xenografts --;Preclinical Drug Evaluation with Human Melanoma Xenografts --;Lung Xenografts as a Predictive Screen for Antineoplastic Agents --;Chemotherapy Studies in Human Non-Small Cell Lung Cancer Xenografts Transplanted in Immune-Deprived Mice --;Establishment and Response to Chemotherapy of Human Cervical Carcinoma Xenografts --;The Usefulness of the Nude Mouse Model for Predicting the Chemosensitivity of Human Tumors. Studies in Malignant Melanoma --;IV. Preclinical Evaluation of Analogs of Known Anticancer Agents --;Screening of Analogs in Human Ovarian Cancer Xenografts --;Predictability of Clinical Response of Several Human and Murine Tumor Models to Four Anthracycline Derivatives --;V. New Drugs --;Activity of Six New Drugs in Head and Neck Cancer Xenografts --;Activity of Metallocene Complexes Against Human Tumours Heterotransplanted into Athymic Mice --;VI. Human Tumour Xenografts in the Development of Biological Response Modifiers --;The Effect of Human and Murine Interferons on Human Tumour Xenografts --;Biodistribution and Therapeutic Efficacy of a Monoclonal Antibody-Methotrexate Conjugate in Mice --;The Effect of Interferon-Alpha on the Activity of Cytotoxic Drugs in Bronchial Carcinoma Xenografts --;The Nude Mouse for the Study of Immunotoxins --;VII. Human Tumour Xenografts in Drug Screening --;Proposal for the Application of Xenografts in Screening for New Anticancer Agents and in Selecting Tumor Types for Phase II Clinical Trials --;Human Tumour Xenograft Models for Use with an In Vitro-Based, Disease-Oriented Antitumour Drug Screening Program --;VIII. Importance of Drug Resistance in Screening --;Mechanisms of Drug Resistance in Screening --;Circumvention of Inherent Resistance with Verapamil in a Human Tumour Xenograft --;IX. Proferred Papers at the E.S.O. Seminar --;Clonogenic Assay Screening Study Group (CASSG): Contribution to an EORTC Drug Screening Programme --;Polyamine Uptake by Malignant Brain Tumour Xenografts in Nude Mice --;The Activity for a Novel Niteosourea (TCNU) in Human Lung Cancer Xenografts --;Xenografts in Pharmacologically Immunosuppressed Mice as a Model to Test the Chemotherapeutic Sensitivity of Human Tumours --;New Tissue-Specific Metastasis Models in Adult Nude Mice --;Fractionated Irradiation of Human Tumor Xenografts in Athymic Nude Mice --;An Animal Model for Human Tumor Xenografts --;Xenografted Human Tumors in Preclinical Drug Design --;Growth in Nude Mice of a T-Cell Line from a Case of Acute Lymphoblastic Leukaemia: A Model for Experimental Immunotherapy of Human Neoplasia --;5-Fluorouracil (5-FU) + Cis-diamminedichloroplatinum (DDP) Treatment of Human Colorectal Tumor Xenografts --;Inter and Intra-Tumor Variation in the Response to Chemotherapy of Human Small Cell Carcinoma of the Lung (SCCL) Grown in Nude Mice --;Human Carcinoma Cell Lines Xenografted in Athymic Mice: Biological and Antigenic Characterization of an Intra-Abdominal Model --;Squamous Cell Carcinoma Xenografts as a Model for the Study of Drug-Induced Cell Kinetic Changes in Head and Neck Cancer.
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| Abstract
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Seminar on Human Tumour Xenografts 1986, Milan, Italy. European School of Oncology
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| Subject
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Immunology.
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Medicine.
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Toxicology.
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| LC Classification
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RC271.C5E358 1988
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| Added Entry
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Benjamin Winograd
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Herbert Michael Pinedo
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Michael Peckham
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| Parallel Title
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Seminar on Human Tumour Xenografts 1986, Milan, Italy. European School of Oncology
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