|
" Principles of Metabolic Control in Mammalian Systems "
edited by Robert H. Herman, Robert M. Cohn, Pamela D. McNamara.
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
726870
|
| Doc. No
|
:
|
b546602
|
| Main Entry
|
:
|
edited by Robert H. Herman, Robert M. Cohn, Pamela D. McNamara.
|
| Title & Author
|
:
|
Principles of Metabolic Control in Mammalian Systems\ edited by Robert H. Herman, Robert M. Cohn, Pamela D. McNamara.
|
| Publication Statement
|
:
|
Boston, MA: Springer US, 1980
|
| ISBN
|
:
|
1461330068
|
|
|
:
|
: 1461330084
|
|
|
:
|
: 9781461330066
|
|
|
:
|
: 9781461330080
|
| Contents
|
:
|
1 The Principles of Metabolic Control --;I. The First Fundamental Theorem of Theoretical Biology --;II. The Second Fundamental Theorem of Theoretical Biology -->III. Other Fundamental Theorems of Theoretical Biology --;IV. Summary --;References --;2 Nonequilibrium Thermodynamics, Noncovalent Forces, and Water --;I. Introduction --;II. Stability, Thermodynamics, and Biological Organization --;III. Noncovalent Forces --;IV. Water --;V. Conclusions and Implications --;Appendix I --;Appendix II: Glossary --;References --;3 Enzymes and Coenzymes: A Mechanistic View --;I. Introduction --;II. Chemical Bonding --;III. Chemical Reactions --;IV. The Protein Nature of Enzymes --;V. Enzyme Mechanisms --;VI. Coenzymes --;VII. Evolution of Enzyme Function --;References --;4 Modulation of Enzyme Activity --;I. Introduction --;II. Noncovalent Regulatory Mechanisms --;III. Covalent Regulatory Mechanisms --;IV. Enzyme Synthesis and Degradation --;V. Evaluation of the Physiologic Importance of Regulatory Mechanisms --;VI. Conclusion: An Overview of Regulation --;References --;5 Regulation of Protein Biosynthesis --;I. Introduction --;II. The Mechanism of Protein Biosynthesis --;III. The Regulation of Protein Biosynthesis --;References --;6 Degradation of Enzymes --;I. Introduction --;II. Kinetics of Enzyme Degradation --;III. Techniques for the Measurement of Enzyme Degradation --;IV. Variability of Enzyme Half-Lives --;V. Changes to Degradation Rate Constants --;VI. Intracellular Localization of Degradative Pathways --;VII. Initial Reactions in Enzyme Degradation --;VIII. Conclusions --;References --;7 DNA Replication and the Cell Cycle --;I. Introduction --;II. Chromatin Structure --;III. The Cell Cycle --;IV. DNA Synthesis --;V. Mitosis --;VI. Gene Activation and Inactivation --;VII. Summary --;References --;8 Servomechanisms and Oscillatory Phenomena --;I. Introduction --;II. Feedback and Feedforward Phenomena --;III. Oscillatory Phenomena --;IV. Proposed Physiological Significance of Oscillatory Phenomena --;References --;9 Membrane-Bound Enzymes --;I. Introduction --;II. Membrane Composition and Structure --;III. Endoplasmic Reticulum --;IV. Golgi Apparatus --;V. Mitochondria --;VI. Plasma Membrane --;VII. Temperature Effects --;VIII. Conclusion: Effects of Lipids on Enzymatic Activity --;References --;10 The Importance of Phospholipid-Protein Interactions for Regulation of the Activities of Membrane-Bound Enzymes --;I. Introduction --;II. Effect of Lipid Composition on the Properties of Membranes and Membrane-Bound Proteins --;III. The Effect of Proteins on the Properties of Membrane Lipids --;IV. The Effect of Phospholipids on the Activities of Soluble Enzymes and Proteins --;V. Reconstituted Systems --;VI. Alteration of the Properties of Tightly-Bound Membrane Enzymes by Perturbation of Their Membrane Lipid Environment --;VII. Model for Lipid-Protein Interactions --;VIII. Consideration of Factors Regulating the Activities of Membrane-Bound Enzymes in Vivo --;IX. Conclusions --;References --;11 Membrane Structure and Transport Systems --;I. Introduction --;II. Contact Inhibition and Intercellular Communication --;III. Antigenic and Receptor Sites --;IV. Membrane Structure --;V. Membrane Composition --;VI. Transport Systems --;VII. Summary --;References --;12 Cellular Mechanisms of Secretion --;I. Introduction --;II. Representative Secretory Cells --;III. Membrane Flow and Differentiation --;IV. Membrane Reutilization --;V. The Clinical Importance of Intracellular Membranes for Secretion --;VI. Microtubules --;VII. Mechanisms of Secretory Activation --;VIII. Types of Secretory Discharge --;IX. Summary --;References --;13 Compartmentation and Its Role in Metabolic Regulation --;I. Introduction --;II. Nature of Intracellular Compartments --;III. Zymogen Activation and Compartmentation --;IV. Membrane Permeability and the Movement of Molecules in the Cell --;V. Examples of the Role of Compartmentation in the Regulation of Energy Metabolism --;VI. Conclusions --;References --;14 The Mechanism of Action of Hormones --;I. Introduction --;II. Hormones --;15 The Biochemical Basis of Disease --;I. Introduction --;II. The Biochemical Basis of Disease --;III. Therapeutic Approaches to Disease --;References.
|
| Abstract
|
:
|
In this work we present the basic principles of metabolic control which we hope will serve as a foundation for the vast array of factual matter which the biochemist and the physician engaged in metabolic research must accumulate.
|
| Subject
|
:
|
Life sciences.
|
| LC Classification
|
:
|
QP171.E358 1980
|
| Added Entry
|
:
|
Pamela D McNamara
|
|
|
:
|
Robert H Herman
|
|
|
:
|
Robert M Cohn
|
| |