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" Neuroblastoma : "
Judy S E Moyes
Document Type
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BL
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Record Number
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727364
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Doc. No
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b547096
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Main Entry
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Judy S E Moyes
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Title & Author
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Neuroblastoma : : mibg in its diagnosis and management.\ Judy S E Moyes
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Publication Statement
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[Place of publication not identified]: Springer, 2013
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ISBN
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1447116747
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: 9781447116745
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Contents
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1 An Overview of Neuroblastoma.- Pathology.- Clinical Features.- Diagnostic Features.- Haematology and Biochemistry.- Histopathology.- Radiological Studies.- Clinical Staging.- Prognostic Features.- Treatment.- 2 Chemistry and Pharmacy of mIBG.- Pharmacology.- Radiolabelled mIBG Products.- Formulations and Stability of mIBG.- Toxicology.- 3 Techniques for Imaging with mIBG.- Patient Preparation.- Sedation.- Thyroid Blockade.- Medicines which Interfere with Uptake of mIBG.- Radiopharmaceuticals.- Choice of Radionuclide.- Activity of Radiopharmaceutical.- Gamma Camera Technique.- Collimator.- Quality Control.- Energy Windows.- Administration of mIBG.- Planar Imaging.- Single-photon Emission Computed Tomography.- Hard Copy.- 4 The Normal Pattern of Distribution of mIBG in Children with a History of Cancer.- Normal Distribution.- The Thyroid Gland.- The Adrenal Gland.- The Liver.- The Spleen.- The Kidneys and Bladder.- The Gastrointestinal Tract.- The Lung.- The Heart.- The Salivary Glands, Nasopharynx and Lacrimal Glands.- The Bone Marrow.- Bone.- Normal mIBG Studies in Children of Different Ages.- 5 Case Studies with Abnormal Uptake of mIBG.- 6 Radiation Dosimetry of Radioiodine-Labelled mIBG.- Review of Radionuclide Dosimetry.- The Physical Properties of 123I and 131I.- Calculation of Absorbed Dose in Children.- Dose Received in Diagnostic Studies.- Dose Received During Therapy.- 7 Practical Aspects of Targetted Radiotherapy with mIBG.- General Principles.- Principles of Therapy with mIBG.- Selection of Patients for mIBG Therapy.- The mIBG Therapy Room.- Patient Investigations Before Treatment.- Drugs which Interfere with mIBG Uptake.- Thyroid Blockade.- Selection of Activity of mIBG to Administer.- Sedation of Patients During Therapy.- Practical Considerations During Administration of mIBG.- Radiation Protection Guidelines.- Discharge after mIBG Therapy.- Appendices.- Appendix A: OPEC Chemotherapy.- Appendix B: High-Dose Melphalan followed by Autologous Bone Marrow Rescue.- Appendix C: Sedation for Children Undergoing mIBG Scintigraphy.- Appendix D: Thyroid Gland Blockade for mIBG Scintigraphy and Targetted Radiotherapy.- Appendix E: Drugs which Interfere with mIBG Studies.- Appendix F: Modified OPEC Chemotherapy.
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LC Classification
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RC280.N4J839 2013
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Added Entry
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Judy S E Moyes
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