| Document Type
|
:
|
BL
|
| Record Number
|
:
|
728084
|
| Doc. No
|
:
|
b547821
|
| Main Entry
|
:
|
edited by John D. Lambris and V. Michael Holers.
|
| Title & Author
|
:
|
Therapeutic interventions in the complement system\ edited by John D. Lambris and V. Michael Holers.
|
| Publication Statement
|
:
|
Totowa, N.J.: Humana Press, ©2000.
|
| Series Statement
|
:
|
Contemporary immunology, 9.
|
| Page. NO
|
:
|
(ix, 259 pages) : illustrations
|
| ISBN
|
:
|
058539511X
|
|
|
:
|
: 0896035875
|
|
|
:
|
: 1468496123
|
|
|
:
|
: 1592590179
|
|
|
:
|
: 9780585395111
|
|
|
:
|
: 9780896035874
|
|
|
:
|
: 9781468496123
|
|
|
:
|
: 9781592590179
|
| Contents
|
:
|
1 Complement as a Regulatory and Effector Pathway in Human Diseases --;2 The Regulation of C1 Activation and its Role in Disease --;3 Inhibition of Complement Serine Proteases as a Therapeutic Strategy --;4 Complement Inhibitors Targeting C3, C4, and C5 --;5 Complement Anaphylatoxins (C3a, C4a, C5a) and Their Receptors (C3aR, C5aR/CD88) as Therapeutic Targets in Inflammation --;6 Modulation of Disease Using Recombinant Human Endogenous Complement Inhibitors --;7 Roles of Integrins CR3 and CR4 in Disease and Therapeutic Strategies --;8 Inhibition of Complement in the Membrane Attack Pathway --;9 Evaluation of Complement Inhibitors --;10 Use of Animal Models to Define Complement Functions.
|
| Abstract
|
:
|
A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients.
|
| Subject
|
:
|
Anti-inflammatory agents.
|
| Subject
|
:
|
Complement inhibition.
|
| Subject
|
:
|
Inflammation -- Mediators.
|
| LC Classification
|
:
|
QR185.8.C6E358 2000
|
| Added Entry
|
:
|
J D Lambris
|
|
|
:
|
V Michael Holers
|