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" Shock, sepsis, and organ failure "
First Wiggers Bernard Conference. Günther Schlag ... (eds.).
Document Type
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BL
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Record Number
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730393
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Doc. No
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b550156
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Main Entry
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First Wiggers Bernard Conference. Günther Schlag ... (eds.).
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Title & Author
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Shock, sepsis, and organ failure\ First Wiggers Bernard Conference. Günther Schlag ... (eds.).
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Publication Statement
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Berlin u.a.: Springer, 1990
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Page. NO
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x, 660 Seiten : Illustrationen, Diagramme
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ISBN
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0387524959
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: 3540524959
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: 9780387524955
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: 9783540524953
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Notes
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Literaturangaben.
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Contents
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Carl J. Wiggers.- Claude Bernard.- 1. What is Multi-Organ-Failure - Is it a Sequence of Organ Failures or a Systemic Disease?.- Clinical Manifestations and Sequences of Organ Failure.- Discussion.- The Specific Role of ARDS in the Development of Multiple Organ Failure.- Discussion.- Quantification of Organ Failure.- Discussion.- The Metabolic Basis of the Septic Multiple Organ Failure Syndrome: Abnormal Energetic Fuel Control, Pathophysiologic Proteolysis and Futile Cycling of Hepatically Synthesized Substrates.- Discussion.- Humoral and Cellular Activation in Blood Leading to Organ Failure.- Discussion.- Endothelium as the Interface Between Blood and Organ in the Evolution of Organ Failure.- Discussion.- Cellular Metabolic Responses in Endotoxemia, and a Hypothesis for the Mechanism of Hepatic Failure in Endotoxic Shock.- Discussion.- 2. Cellular Events in Trauma and Sepsis - Suppression Versus Activation or Both ?.- Posttraumatic Immune Suppression as Initiator of Organ Failure.- Humoral Factors in Immune Suppression After Injury.- Discussion.- Activation of Neutrophils and the Role of Eicosanoids in the Initiation of Organ Failure.- Discussion.- Role of Xanthine Oxidase-Derived Oxidants and Granulocytes in Ischemia/Reperfusion.- Discussion.- Role of Proteinases in the Pathophysiology of Organ Failure.- Discussion.- Activation of Cellular Membrane Receptors; Intracellular Messengers and Mediators of the Response to Injury.- Discussion.- 3. Mediators of Organ Failure - Are LPS or Sepsis Necessary ?.- Experimental Induction of Whole Body Inflammation Leads to ARDS, Multiple Organ Failure and Sepsis. The ZIGI-Model in Rats and Mice.- Discussion.- Endotoxin-Initiated Organ Failure Responses.- Discussion.- Through a Glass Darkly: The Gut in Multiple Organ Failure.- Discussion.- Changes in Mesenteric Blood Flow Affects Translocation in Sheep.- Discussion.- Antagonists of Platelet-Activating Factor as Potential Therapeutic Agents in Shock.- IL-1 and TNF: Mediators of LPS-Induced Neutrophil Emigration and Thrombosis.- Discussion.- 4. Conference Summary and Concluding Remarks.- Multiple Organ Failure as a Systemic Disease of Host-Defense Failure.- Final Discussion.
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Subject
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Organversagen.
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Subject
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Schock.
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Subject
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Sepsis.
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LC Classification
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RC182.S4F577 1990
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Added Entry
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Günther Schlag
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Wiggers Bernard Conference (1, 1989, Hof, Salzburg)
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