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" Novel pharmacological interventions for alcoholism "
C.A. Naranjo, Edward M. Sellers, editors.
Document Type
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BL
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Record Number
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730676
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Doc. No
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b550442
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Main Entry
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C.A. Naranjo, Edward M. Sellers, editors.
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Title & Author
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Novel pharmacological interventions for alcoholism\ C.A. Naranjo, Edward M. Sellers, editors.
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Publication Statement
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New York: Springer, ©1992.
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Page. NO
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(xv, 378 pages) : illustrations
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ISBN
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1461228786
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: 9781461228783
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Notes
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Based on papers delivered at a meeting of the Fifth Congress of the International Society for Biomedical Research on Alcoholism, held June 16-17, 1990.
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Contents
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Novel Pharmacological Interventions for Alcoholism; Copyright; Acknowledgments; Contents; Contributors; Part I General Methodologic Issues; 1 Animal Models for Testing Drug Effects on Alcohol Consumption; 2 Animal Models for Screening Drugs to Decrease Alcohol Consumption; 3 Medications for Alcohol Abuse and Dependence: Methodology for Clinical Studies; 4 Some Issues in the Evaluation of a Pharmacotherapy of Alcoholism; Part II Serotonin and Alcohol Consumption; 5 Serotonin and Alcohol Consumption; 6 Serotonergic and Dopaminergic Involvement in Ethanol Intake 7 Serotonin and Alcohol Consumption8 Basic and Clinical Studies on Serotonin, Alcohol, and Alcoholism; 9 Evaluation of the Effects of Serotonin Uptake Inhibitors in Alcoholics: A Review; Part III Opioids and Alcohol Consumption; 10 Opioids Modulate Rats' Propensities to Take Alcoholic Beverages; 11 The Enkephalinergic System and Maintenance of Ethanol Drinking; 12 The Relationship of Alcohol Drinking and Endogenous Opioids: The Opioid Compensation Hypothesis; 13 Naltrexone in the Treatment of Alcohol Dependence: Preliminary Findings Part IV The Role of Other Neurotransmitters in Regulating Alcohol Intake14 Neurotransmitter Systems Regulating Alcohol Intake; 15 Agents Which Modify Channels as Potential Treatments in Alcohol Withdrawal; 16 Management of Alcohol Consumption with Angiotensin Converting Enzyme Inhibitors: A Review of the Animal Findings; 17 Enalapril Does not Decrease Alcohol Intake in Normotensive Alcoholics; Poster Papers: General Methodologic Issues; Rational vs. reflexive alcohol drinking; RATS' INTAKES OF DIFFERENT ALCOHOLIC BEVERAGES DRUG-INDUCED SPECIFIC AND NONSPECIFIC CHANGES IN VOLUNTARY ETHANOL INTAKE BY RATSRationale for Alcoholism Treatment Based on Inhibition of Aldehyde Dehydrogenase; THE EFFECT OF LOW ALCOHOL BEVERAGES ON ALCOHOLISM LEVELS IN CANADA IN 1986; ALCOHOLISM, ANTISOCIAL BEHAVIOR, AND FAMILY HISTORY: A SYNOPSIS; PERCEPTION OF WHETHER DRUG OR PLACEBO HAS BEEN ADMINISTERED IS A DETERMINANT OF DRINKING REDUCTION; DISULFIRAM TREATMENT OF ALCOHOLISM; CONTROLLED RELEASE DISULFIRAM (DS) IMPLANT.; DEPOT DISULFIRAM: PHARMACOKINETICS AND CLINICAL EFFECTS DURING 28 DAYS FOLLOWING A SINGLE SUBCUTANEOUS DOSE MILDLY INTOXICATING LEVELS OF ALCOHOL PRODUCFS DIRECT MYOCARDIAL DEPRFSSION ON LEFT VENTRICULAR PERFORMANCEA HUMAN MODEL FOR TESTING DRUG-INDUCED CONCOMITANT VARIATIONS IN ALCOHOL CONSUMPTION AND DESIRE TO DRINK*; Poster Papers: Serotonin and Alcohol Consumption; MIANSERIN, A SEROTONERGIC ANTAGONIST, AND INTAKE OF AN ALCOHOLIC BEVERAGE; EFFECTS OF THE 5-HT UPTAKE INHIBITOR, SERTRALINE, ON ETHANOL, WATER AND FOOD CONSUMPTION; FLUVOXAMINE IS POORLY TOLERATED BY ALCOHOLICS; Poster Papers: Opioids and Alcohol Consumption; EFFECTS OF DIFFERENTIAL HANDLING ON RATS' INTAKE OF ALCOHOL
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Abstract
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Novel Pharmacological Interventions for Alcoholism identifies priorities for focusing alcoholism and addiction research efforts during the coming years. A number of important issues concerning methodology, mechanisms, clinical evaluation, and pharmaceutical aspects are discussed.
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Subject
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Alcoholism -- Animal models -- Congresses.
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Subject
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Alcoholism -- Chemotherapy -- Congresses.
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Subject
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Alcoholism -- Research -- Methodology -- Congresses.
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LC Classification
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RC565.C363 1992
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Added Entry
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C A Naranjo
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E M Sellers
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