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" G proteins, receptors, and disease "
edited by Allen M. Spiegel.
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BL
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| Record Number
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730733
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b550499
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| Main Entry
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edited by Allen M. Spiegel.
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| Title & Author
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G proteins, receptors, and disease\ edited by Allen M. Spiegel.
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| Publication Statement
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Totowa, N.J.: Humana Press, ©1998.
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| Series Statement
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Contemporary endocrinology (Totowa, N.J.), 6.
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| Page. NO
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(x, 324 pages) : illustrations (some color).
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| ISBN
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1461218020
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: 1461272904
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: 9781461218029
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: 9781461272908
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| Contents
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1 Introduction to G-Protein-Coupled Signal Transduction and Human Disease --;2 Albright Hereditary Osteodystrophy, Pseudohypopara-thyroidism, and Gs Deficiency --;3 Gas-Activating Mutations: A Cause of Acromegaly, Thyroid Adenomas, Fibrous Dysplasia, and the McCune-Albright Syndrome --;4 Ulcerative Colitis in Mice Lacking G?i2 --;5 G Proteins Regulating Insulin Action and Obesity: Analysis by Conditional, Targeted Expression of Antisense RNA in vivo --;6 G;12- and G?3- Subunits of Heterotrimeric G Proteins : A Novel Family of Oncogenes --;7 Hypo- and Hyperthyroidism Caused by Mutations of the TSH Receptor --;8 Disorders Caused by Mutations of the Lutropin/ Choriogonadotropin Receptor Gene --;9 Inactivating and Activating Mutations of the FSH Receptor Gene --;10 Nephrogenic Diabetes Insipidus and Vasopressin Receptor Mutations --;11 Disorders with Increased or Decreased Responsiveness to Extracellular Ca2+ Owing to Mutations in the Ca2+0-Sensing Receptor --;12 Constitutively Active PTH/PTHrP Receptors Cause Jansen's Metaphyseal Chondrodysplasia --;13 Mutation of the Growth Hormone-Releasing Hormone Receptor in the little Mouse --;14 Functional Variants of the MSH Receptor (MC1-R), Agouti, and Their Effects on Mammalian Pigmentation --;15 ACTH Resistance Syndromes --;16 Altering Adrenergic Signaling and Cardiac Function in Transgenic Mice --;17 Dopamine Receptors in Human Disease: Lessons from Targeted Mouse Mutants --;18 The?3-Adrenergic Receptor and Susceptibility to Obesity, the Insulin Resistance Syndrome, and Noninsulin-Dependent Diabetes Mellitus.
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| Abstract
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This collection summarizes in-depth the state of knowledge concerning how cells communicate via G-protein-coupled signal transduction and how defects in these proteins and their receptors can cause serious human disease involving many different organ systems.
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| Subject
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Endocrine glands -- Diseases.
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| Subject
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G proteins -- Pathophysiology.
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G proteins -- Physiological effect.
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| LC Classification
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QP552.G16E358 1998
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| Added Entry
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Allen M Spiegel
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