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" Viral proteins counteracting host defenses "
edited by U.H. Koszinowski and H. Hengel.
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BL
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| Record Number
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730846
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b550612
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| Main Entry
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edited by U.H. Koszinowski and H. Hengel.
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| Title & Author
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Viral proteins counteracting host defenses\ edited by U.H. Koszinowski and H. Hengel.
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| Publication Statement
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Berlin ; New York: Springer, ©2002.
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| Series Statement
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Current topics in microbiology and immunology, 269.
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| Page. NO
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(x, 325 pages) : illustrations
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| ISBN
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3642594212
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: 9783642594212
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| Contents
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Strategies for the Identification and Analysis of Viral Immune-Evasive Genes --;Cytomegalovirus as an Example / A. Gutermann, A. Bubeck, M. Wagner, U. Reusch, C. Menard, U.H. Koszinowski --;Avoiding Proteasomal Processing: The Case of EBNA1 / N.P. Dantuma, A. Sharipo, M.G. Masucci --;The HCMV Gene Products US2 and US11 Target MHC Class I Molecules for Degradation in the Cytosol / F.J. van der Wal, M. Kikkert, E. Wiertz --;Corking the Bottleneck: The Transporter Associated with Antigen Processing as a Target for Immune Subversion by Viruses / F. Momburg, H. Hengel --;Herpes Viral Proteins Manipulating the Peptide Transporter TAP / E. Reits, A. Griekspoor, J. Neefjes --;Herpes Viral Proteins Blocking the Transporter Associated with Antigen Processing TAP --;From Genes to Function and Structure / D. Bauer, R. Tampe --;Inhibition of the MHC Class II Antigen Presentation Pathway by Human Cytomegalovirus / D.C. Johnson, N.R. Hegde --;Viral Evasion of Natural Killer Cells During Human Cytomegalovirus Infection / V.M. Braud, P. Tomasec, G.W.G. Wilkinson --;Function of CMV-Encoded MHC Class I Homologues / H.E. Farrell, N.J. Davis-Poynter, D.M. Andrews, M.A. Degli-Esposti --;Human Cytomegalovirus Inhibition of Major Histocompatibility Complex Transcription and Interferon Signal Transduction / D.M. Miller, C.M. Cebulla, D.D. Sedmak --;Counteraction of Interferon-Induced Antiviral Responses by Herpes Simplex Viruses / D.A. Leib.
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| Abstract
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Since the first observations of viral interference with antigen presentation in the MHC class-I pathway, the field has advanced to a detailed analysis. This text discusses proteasomal degradation of an antigenic viral protein, transfer of the proteasomal cleavage products as peptides and more.
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| Subject
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Immune response.
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Major histocompatibility complex.
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Viral proteins.
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| LC Classification
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QR1.E358 2002
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| Added Entry
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H Hengel
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U H Koszinowski
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