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" Handbook of the Hemopoietic Microenvironment "
edited by Mehdi Tavassoli.
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BL
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731216
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b551002
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| Main Entry
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edited by Mehdi Tavassoli.
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| Title & Author
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Handbook of the Hemopoietic Microenvironment\ edited by Mehdi Tavassoli.
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| Publication Statement
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Totowa, NJ: Humana Press, 1990
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| Series Statement
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Contemporary biomedicine, 9.
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(472 pages)
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| ISBN
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1461244943
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: 1461288452
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: 9781461244943
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: 9781461288459
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| Contents
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Hemopoietic Microenvironments Historical Perspectives, Status, and Projections.- Historical Perspectives, Status, and Projections.- Definition.- Radiation Protection by Marrow Transplantation.- The Spleen Colony Assay.- Antecedents of the Hemopoietic Microenvironment Concept.- Homing.- Unexplained Failure of Marrow Isografts.- Spleen Colony Types.- Decision.- Spleen Colony Retransplantation.- Effect of Erythropoietin Deprivation on Spleen Colony Types.- Visualization of Erythropoietin-Sensitive Stem Cell Colonies.- Decision for Lineage-Specific Differentiation.- Endoclonal Origin of the Second Line of Differentiation.- The Working Hypothesis.- Tests of the Working Hypothesis.- Bone Marrow Colonies and Characteristics.- Hemopoietic Colony Characteristics in Transplanted Spleen or Bone Marrow Stroma.- Whole Spleen Stroma Transplant `Cure' of Sl/Sld Anemia.- Effect of Mouse Hemopoietic Microenvironments on Rat CFU-S.- Microenvironmental Control of Eosinophilic Granulocyte Response to Tetanus Toxoid.- Microenvironmental Control of Mast Cell Differentiation.- Dissecting the Hemopoietic Microenvironment.- Other Evidence of the Roles of Marrow, Spleen, and Thymus Organ Stroma in Hemopoiesis and Lymphopoiesis.- Hemopoiesis on Intraperitoneal Cellulose Acetate Membranes.- CFU-S Heterogeneity.- Reversible Effect of Marrow and Spleen Microenvironments on Thymic Progenitor Cell Differentiation and Proliferation.- Reversible Predisposition of CFU-S for Direction of Differentiation.- Hemopoietic Hormone (Growth Factor) Receptors.- Pluripotency of Hemopoietic CFU-S for Lymphoid Differentiation.- Lymphoid-Inductive Microenvironments.- In Vitro Bone Marrow Cultures.- Early Methods.- The Dexter Method.- The Greenberger Modification.- B-Lymphocyte Cultures.- Distinctive Stromal Cells of Erythroid and Granuloid Spleen Colonies.- Erythroid Colonies.- Granuloid Colonies.- Other Candidate for In Vivo Hemopoietic Microenvironment Stromal Cells.- Hemopoiesis.- Random or Controlled?.- Projections.- Malignancy-Inducing Microenvironments?.- References.- Molecular and Cellular Traffic Across the Marrow Sinuses.- Marrow Structure.- Arterial and Venous Circulation.- Marrow Sinuses.- Marrow Nerves.- Evidence for Discrimination in the Release of Marrow Cells.- Factors Governing Release of Hemopoietic Cells.- Biophysical Properties of Developing Hemopoietic Cells.- Cell Releasing Factors.- Control of Blood Flow in Marrow.- The Anatomical Process of Release.- Ultrastructural Features of Reticulocyte Egress.- Modeling Reticulocyte Egress.- Ultrastructural Features of White Cell Egress.- Ultrastructural Features of Platelet Release.- Release of Immature Cells in Healthy Subjects.- Release of Immature Cells in Pathological States.- Release from and Reentry into Marrow of Stem Cells and Progenitor Cells.- References.- In Vivo Microscopy of Hemopoietic Tissue.- In Vivo Microscopic Methods.- Basic Methods.- Transillumination Methods.- Epi-illumination Methods.- In Vivo Microscopic Studies of Hemopoietic Tissue.- References.- Fatty Involution of Marrow and the Role of Adipose Tissue in Hemopoiesis.- Distribution of Red and Yellow Marrow.- The Role of Bone.- Ectopic Implantation of Bone Marrow.- Marrow Adipocyte.- Development.- Structure.- Function.- Distinct from Extramedullary Adipocytes.- Functional Differences.- Heterogeneity of Marrow Adipocytes.- Marrow Adipocytes in Culture.- Conclusions.- References.- Hematopoiesis on Artificial Membranes.- Hematopoiesis on Flat CEM.- Hematopoiesis On Stromally-Enriched, IP-Implanted Tubular CEM.- Hematopoiesis and Proteoglycans.- Role of Bone and Tooth Matrix Proteins in Hematopoiesis.- Irradiation of Stromal Cells.- Studies of Scraped, Devitalized, and Reimplanted CEM.- Overall Perspective and Significance of Hematopoiesis on CEM.- References.- Cellular Components of Stroma In Vivo in Comparison with In Vitro Systems.- Cellular Components of the Stroma.- Reticular Cells In Vivo.- Fibroblastic Reticular Cells in Long-Term Cell Culture.- Macrophages.- Macrophages of Bone Marrow Origin in Long-Term Culture.- References.- Stromal Cells in Long-Term Bone Marrow Cultures.- Cell Types in Adherent Layer.- Growth Factor Production by Adherent Cells.- Studies in Other Species Including Human.- Lymphoid Growth and Long-Term Culture.- TC-1 Cell Line.- Hypothesis.- References.- Cultured Stromal Cell Lines from Hemopoietic Tissues.- The Hemopoietic Microenvironment.- Putative Functions.- Nature of Stromal Cells.- Primary Cultures of Bone Marrow Stromal Cells.- The Requirement for Permanent Stromal Cell Lines.- Hemopoietic Stromal Cell Lines.- Derivation.- Growth.- Morphology.- Adipogenesis.- Cytoplasmic Enzymes.- Extracellular Matrix.- Cell Surface Markers.- Classification.- Long-Term In Vitro Hemopoiesis.- Colony Stimulating Factors (CSF).- Differentiation-Restraining Activities.- Other Regulators of Hemopoiesis.- Leukemia Cell Inhibitory Activity (LCIA).- Promotion of Leukemia Cell Growth.- Promoters of Leukemia Cell Differentiation.- Transplantation and Tumorigenesis.- Modulation of In Vitro Functions.- Tissue and Cell-Lineage Specificity.- Summary.- References.- Cellular Interactions in the Regulation of Human Hemopoiesis In Vitro.- Normal Hemopoiesis.- Role of T-Cells.- Role of Monocytes.- Role of NK Cells.- Abnormal Hemopoiesis.- Aplastic Anemia.- References.- The Collagenous Hemopoietic Microenvironment.- The Genetically-Distinct Types of Collagen.- Type I Collagen.- Type II Collagen.- Type III Collagen.- Type IV Collagen.- Type V Collagen.- Type VI Collagen.- Type VII Collagen.- Type VIII Collagen.- Type IX Collagen.- Type X Collagen.- Type XI Collagen.- Collagenous Bone Marrow Stroma.- Synthesis of Collagenous Matrix by Stromal Cells of the Bone Marrow.- Bone Marrow Collagen in Hematologic Disorders.- Myelofibrosis.- Future Prospects.- References.- The Hemopoietic Extracellular Matrix.- The Role of the Extracellular Matrix in Regulating Cell Growth and Differentiation.- Characterization of Noncollagenous Extracellular Matrix Macromolecules Found in Bone and Bone Marrow.- Fibronectin.- Laminin.- Proteoglycans.- Other Extracellular Matrix Proteins of Bone and Bone Marrow.- Summary of Extracellular Matrix Macromolecules Found in Bone and Bone Marrow.- Identification of Extracellular Matrix Proteins in the Stroma of Long-Term Bone Marrow Cell Cultures.- Fibronectin and Laminin.- Proteoglycans.- Summary of Extracellular Matrix Glycoproteins and Proteoglycans Produced in Long-Term Bone Marrow Cultures.- The Role of Extracellular Matrix Components in Regulating Hemopoiesis in Long-Term Bone Marrow Cultures.- Reconstitution of Bone and Bone Marrow In Vivo by Ectopic Implantation of Devitalized, DemineralizedBone Matrix.- Studies of the Abnormal Hemopoietic Microenvironment of Sl/Sld Mice.- Summary.- References.- Bone Marrow Microenvironment Clinical Observations.- Clinical Implications.- Functional Abnormalities of Cellular Components of Bone Marrow Microenvironment.- T-Lymphocytes.- Bone Marrow Macrophages.- Bone Marrow Fibroblasts.- References.
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| Subject
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Hematology.
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| Subject
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Medicine.
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| LC Classification
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QP92.E358 1990
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| Added Entry
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Mehdi Tavassoli
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