| Document Type
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BL
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| Record Number
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731352
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| Doc. No
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b551138
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| Main Entry
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edited by Matti S. Aapro.
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| Title & Author
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Innovative Antimetabolites in Solid Tumours\ edited by Matti S. Aapro.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1994
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| Series Statement
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ESO Monographs, European School of Oncology.
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| Page. NO
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(vii, 59 pages 4 illustrations)
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| ISBN
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3642792006
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: 9783642792007
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| Contents
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Antimetabolites: Historical Perspectives --;Preclinical Characteristics of Cytarabine, Gemcitabine, Fludarabine and Cladribine: Relevance for Clinical Studies --;Thymidylate Synthase Inhibitors, Modulation of 5-Fluorouracil and Folate Analogues --;A Review of Fludarabine and Cladribine in Solid Tumours --;Advanced Breast Cancer: Experience with Gemcitabine --;Gemcitabine in Ovarian Cancer --;Gemcitabine Therapy in Non-Small Cell Lung Cancer: A Review --;Chemotherapy in Advanced Non-Small Cell Lung Cancer. Changes in Performance Status and Tumour-Related Symptoms --;Safety Profile of Gemcitabine, Fludarabine and Cladribine.
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| Abstract
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The field of antimetabolites from basic science to clinical application is covered in this book. This continously evolving field represented the first kind of effective chemotherapy for human cancer. Aspects of biomodulation of 5-fluorouracil led to the recent development of agents such as gemcitabine, cladribine and fludarabine. The reader gains a good overview of a very important area for cancer treatment in one single volume.
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| Subject
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Medicine.
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| Subject
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Oncology.
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| Subject
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Toxicology.
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| LC Classification
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RC271.A68E358 1994
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| Added Entry
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Matti S Aapro
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