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" Biological Basis of Oncologic Thermotherapy "
edited by Michel Gautherie.
Document Type
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BL
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Record Number
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731454
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Doc. No
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b551240
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Main Entry
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edited by Michel Gautherie.
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Title & Author
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Biological Basis of Oncologic Thermotherapy\ edited by Michel Gautherie.
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Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1990
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Series Statement
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Clinical thermology., Subseries thermotherapy.
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Page. NO
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(xi, 169 pages 116 illustrations)
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ISBN
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3642749399
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: 9783642749391
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Contents
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1 Biological Basis of Thermotherapy (With Special Reference to Oncology) --;1.1 Introduction --;1.2 Methods of Hyperthermia Treatment --;1.3 Heat Transfer to Tissues and Temperature --;1.4 Biological Basis for the Action of Hyperthermia and of Combination with Ionizing Radiation --;1.5 Mechanisms of Action in Cell Killing --;1.6 Responses of Normal Tissues and Tumors --;1.7 Combination of Hyperthermia and Drugs --;1.8 Conclusions --;References --;2 Pathophysiological Mechanisms of Hyperthermia in Cancer Therapy --;2.1 Effects of Hyperthermia on Blood Flow Rates and Microcirculation in Normal and Neoplastic Tissues --;2.2 Microvascular Permeability in Tumors --;2.3 Temperature Distribution in Tumors --;2.4 Hyperthermia-Induced Changes in Nutrient and Oxygen Consumption Rates in Tumors --;2.5 Impact of Hyperthermia on the Cellular Microenvironment in Tumors --;2.6 Effect of Hyperthermia on Intracellular Ion Concentrations --;2.7 Conclusions --;References --;3 The Heat Shock Response: Events Before, During, and After Gene Activation --;3.1 Introduction --;3.2 Events Before Gene Activation --;3.3 Events During and Immediately After Gene Activation --;3.4 Late Events --;3.5 Conclusion --;References.
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Abstract
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Studies on the effects of hyperthermia have aroused great interest in recent years. However, since it has been shown that radiation-induced cell killirtg can be remarkably enhanced by hyperthermia, many investigations have been performed with cells in vitro, tumors in situ, and normal tissues.
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Subject
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Medicine.
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Subject
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Oncology.
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Subject
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Radiotherapy.
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LC Classification
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RC271.T5E358 1990
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Added Entry
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Michel Gautherie
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