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" Mechanisms in B-Cell Neoplasia 1994 "
edited by Michael Potter, Fritz Melchers.
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BL
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733002
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b552795
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| Main Entry
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edited by Michael Potter, Fritz Melchers.
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| Title & Author
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Mechanisms in B-Cell Neoplasia 1994\ edited by Michael Potter, Fritz Melchers.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1995
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| Series Statement
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Current topics in microbiology and immunology, 194.
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(xxv, 458 pages 152 illustrations, 12 illustrations in color.)
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| ISBN
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3642792758
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: 9783642792755
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| Contents
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The "Myeloma" Clone --;Detection of Peripheral Blood Myeloma Cells by Three-Color Flow Cytometry --;Detection of B-Cells Clonally Related to the Tumor Population in Multiple Myeloma and MGUS --;The Blood B-Cells and Bone Marrow Plasma Cells in Patients with Multiple Myeloma Share Identical IgH Rearrangements --;Multiple Myeloma Clones are Derived from a Cell Late in B Lymphoid Development --;The Myeloma/Plasmacytoma Phenotype --;Multiple Myeloma --;Recent Developments in Molecular and Cellular Biology --;Potential Role of CD28-B7 Interactions in the Growth of Myeloma Plasma Cells --;B-1 (CD5+) B-Cells as a Marker of Immune Dysregulation in Multiple Myeloma --;Genes Expressed Selectively in Murine and Human Plasma Cell Neoplasms --;Molecular and Biological Role of CD40 in Multiple Myeloma --;The Proliferation-Associated Cytosolic Protein Lap 18 (stathmin) is Expressed at Atypically Low Levels in BALB/c Plasmacytom Cells --;Plasmacytoma Induction in Mice --;Induction of Plasmacytomas in Genetically Susceptible Mice with Silicone Gels --;Strain-Related Cellular Mechanisms as a Determinant for Susceptibility and Resistance to PC Induction --;Human and Mouse B-Cell Lymphomas --;Alterations of the BCL-6 Gene in Diffuse Large-Cell Lymphoma --;Classification of Mouse Lymphomas --;The Natural History of a Lymphoproliferative Disorder in Aged NZB Mice --;EBV Infection of B-CLL Cells in Vitro Potentiates Their Allostimulatory Capacity if Accompanied by Acquisition of the Activated Phenotype --;A New Form of Epstein-Barr Virus Latency in vivo --;Pharmacologic Activation of Expression of Immunodominant Viral Antigens: A New Strategy for the Treatment of Epstein-Barr-Virus-Associated Malignancies --;Rapid Identification of Novel Human Lymphoid-Restricted Genes by Automated DNA Sequencing of Subtracted cDNA Libraries --;Tumorigenesis in Mice with an SV40T Antigen Transgene Driven by the Immunoglobulin?1 Heavy Chain Germline Promoter --;Circulating B-Cells in Follicular Non-Hodgkin's Lymphoma Show Variant Expression of L-Selectin Epitopes --;Light Chain Loss and Reexpression Leads to Idiotype Switch. Surrogate Light Chains are Probably Responsible for this Process --;Growth Regulation: IL-6 --;Regulation of Terminal differentiation of Human B-Cells by IL-6 --;Sequence, Expression and Function of an mRNA Encoding a Soluble Form of the Human lnterleukin-6 Receptor (sIL-6R) --;The Late B-Cell --;CD5 Transgenic Mice --;Activation of B-Cells by sIgM Cross-Linking Induces Accumulation of CD5 mRNA --;GP130 in Human Myeloma/Plasmacytoma --;Analysis of Antigen-Driven Positive and Negative Selection of Phosphocholine-Specific Bone Marrow B-Cells --;Growth Regulation --;C-myc --;Role of the Rel-Family of Transcription Factors in the Regulation of c-myc Gene Transcription and Apoptosis of WEHI231 Murine B-Cells --;c-myc Transcription is Initiated From Po in 70% of Patients with Multiple Myeloma --;Clustered Mutations in the Transcritpional Activation Domainof Myc in 8q24 Translocated Lymphomas and their Functional Consequences --;Association with C-Myc: An Alternate Mechanism for c-Myc Function --;The Role of Ornithine Decarboxylase in c-Myc-lnduced Apoptosis --;Growth Factor Regulation of Cell Cycle Progression and Cell Fate Determination --;Growth Regulation: Apoptosis, BCL-2, Dormancy --;Defective Apoptosis due to Bcl-2 Overexpression May Explain Why B-CLL Cells Accumulate in G0 --;Lyn Tyrosine Kinase Signals Cell Cycle Arrest in Mouse and Human B-Cell Lymphoma --;A Link Between the Antioxidant Defense System and Calcium: A Proposal for the Biochemical Function of Bcl-2 --;Heterodimerization with Bax is Required for Bcl-2 to Repress Cell Death --;Growth Regulation: Cyclin D1, ABL --;Mantle Cell/Centrocytic Lymphoma: Molecular and Phenotypic Analysis Including Analysis of the bcl-1 Major Translocation Cluster by PCR --;Cyclin D1 as the Putative bcl-1 Oncogene --;Pre-B-Cells Transformed by ts Abelson Virus Rearrange? and? Genes in Early G1 --;Development of btk Transgenic Mice --;Genomic Instability: General Topics --;Genomic Instability in B-Cells and Diversity of Recombinations That Activate c-myc --;Broken-Ended DNA and V(D)J Recombination --;Mutations in the Coding Region of c-myc Occur Independently of Mutations in the Regulatory Regions and are Predominantly Associated with myc/lg Translocation --;The Generation of Pvt-1/Ck Chimeric Transcripts as an Assay for Chromosomal Translocations in Mouse Plasmacytomas --;Interacisternal A-particle (IAP) Genes show Similar Patterns of Hypomethylation in Established and Primary Mouse Plasmacytomas --;Regulatory Elements in the Immunoglobulin Kappa Locus Induce c-myc Activation in Burkitt's Lymphoma Cells --;Genomic Instability: Heavy Chain Switch Related Problems --;Illegitimate Recombinations Between c-myc and Immunoglobulin Loci Are Remodeled by Deletions in Mouse Plasmacytomas But Not in Burkitt's Lymphomas --;Sy3 SNIP and SNAP Binding Motifs are Occupied in vivo in Mitogen Activated l.29? + Cells --;Chromosomally Integrated Retroviral Substrates are Sensitive Indicators of an Antibody Class Switch Recombinase-Like Activity --;The Role of BSAP in Immunoglobulin Isotype Switching and B-Cell Proliferation.
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| Abstract
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The 12th Workshop on "Mechanisms in B-Cell Neoplasia" continues this series of meetings on intriguing new developments in human and experimental B-cell tumors. The integration of knowledge from basic B-cell biology to the clinical problems of multiple myelomas, follicular lymphoma, mantle cell lymphoma and B-CLL present the challenges that were discussed in the meeting. The discussion focusses on: - Cellular components of the "myeloma clone"--Genomic instability in B-cells and B-cell tumors - The CD5 antigen and B1 cells - Regulation of cell cycle and apoptosis - Role of IL-6, BCL-2, BCL-1, myc in B-cell development.
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Immunology.
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Medical virology.
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Medicine.
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| LC Classification
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QR180.E358 1995
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| Added Entry
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Fritz Melchers
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Michael Potter
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