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" Neutralization of Animal Viruses "
by Nigel J. Dimmock.
Document Type
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BL
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Record Number
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734047
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Doc. No
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b553873
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Main Entry
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by Nigel J. Dimmock.
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Title & Author
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Neutralization of Animal Viruses\ by Nigel J. Dimmock.
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Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1993
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Series Statement
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Current topics in microbiology and immunology, 183.
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Page. NO
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(VII, 149 pages 10 illustrations)
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ISBN
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3540560300
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: 3642778496
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: 3642778518
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: 9783540560302
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: 9783642778490
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: 9783642778513
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Contents
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1 Introduction --;2 Immunoglobulin G Neutralization by Inhibition of Attachment of Virus to the Cell --;3 Immunoglobulin G Neutralization Which Does Not Inhibit Attachment of Virus to the Cell --;4 Immunoglobulin G Neutralization by Aggregation of Virions . . --;5 Immunoglobulin G Neutralization Mechanisms which Operate After Attachment of the Virus-Antibody Complex to a Cell Receptor Unit --;5.1 Inhibition of Fusion at the Plasma Membrane --;5.2 Inhibition of Endocytosis --;5.3 Inhibition of Fusion of Viral and Cellular Membranes --;5.4 Inhibition of Non-fusion Uncoating --;5.5 Inhibition of Events which Occur After Primary Uncoating --;6 Neutralization which Occurs by Virus Binding Antibody After It Has Attached to a Cell --;7 Role of the Cell in Neutralization --;8 Antibody-Dependent Enhancement of Infectivity by Neutralizing Antibody: Fc and Complement Receptors --;9 Neutralization by Polymeric Immunoglobulin A --;10 Neutralization by Immunoglobulin M --;11 The Relevance of Immunoglobulin Isotype to Neutralization --;12 Viral Carbohydrates, Proteins and Neutralization --;12.1 Carbohydrates and Neutralization --;12.2 Proteinsand Neutralization --;13 Properties of Protein and Peptide Antigens Which Elicit Neutralizing Antibody --;14 Neutralization In Vivo --;15 Complement and Neutralization --;16 Neutralization by Inhibition of Release of Progeny Virus from the Infected Cell --;17 Changes in Virus Proteins and Virion Structure on Binding Antibody, Including Synergistic Neutralization --;18 Reversibility of Neutralization --;19 Neutralization by Fragments of Antibody --;20 Quantitative Aspects of Neutralization --;21 Unconventional Neutralization --;21.1 Genetic Engineering of Antibodies and Viruses --;21.2 Anti-idiotype Antibodies and Neutralization --;22 The Evolutionary Significance of Neutralization Sites --;22.1 Why Do Viruses Have Neutralization Sites? --;22.2 Strategies which Avoid or Minimize Expression of, or Response, to Neutralization Sites --;23 Neutralization of Poliovirus and Rhinovirus: A Summary --;23.1 Introduction --;23.2 Attachment --;23.3 Internalization --;23.4 Post-internalization --;23.5 Aggregation --;23.6 Conformational Changes on Binding Antibody --;24 Neutralization of Type a Influenza Virus by Immunoglobulins M, A and G: A Summary --;24.1 Introduction --;24.2 IgM Neutralization --;24.3 IgA Neutralization --;24.4 IgG Neutralization --;24.5 Discussion --;25 Neutralization of HIV-1: A Summary --;26 Conclusions --;References.
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Abstract
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Understanding neutralization is particularly relevant to an appreciation of the interaction between a virus and its antibody-synthesizing host since it is likely that viruses and the antibody system have evolved in response to reciprocally imposed selective pressures.
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Subject
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Immunology.
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Subject
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Medicine.
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Subject
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Microbiology.
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Added Entry
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Nigel J Dimmock
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