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" Novel Inhibitors of Leukotrienes "
edited by Giancarlo Folco, Bengt Samuelsson, Robert C. Murphy.
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BL
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| Record Number
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734175
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| Doc. No
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b554002
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| Main Entry
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edited by Giancarlo Folco, Bengt Samuelsson, Robert C. Murphy.
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| Title & Author
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Novel Inhibitors of Leukotrienes\ edited by Giancarlo Folco, Bengt Samuelsson, Robert C. Murphy.
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| Publication Statement
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Basel: Birkhäuser Basel : Imprint : Birkhäuser, 1999
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| Series Statement
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PIR (Series)
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| Page. NO
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(xii, 347 pages)
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| ISBN
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3034887035
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: 9783034887038
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| Contents
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5-Lipoxygenase --;LTC4 synthase: A key enzyme in cysteinyl leukotriene formation --;Leukotriene A4 hydrolase: A key enzyme in chemotactic leukotriene formation --;Metabolism of leukotrienes and formation of new leukotriene structures --;Receptors for cysteinyl-leukotrienes: Targets for new drugs --;Targeted disruption of 5-lipoxygenase --;Transcellular biosynthesis of leukotrienes: A unique mode of cell communication --;Physiological and pathophysiological activities of leukotrienes --;Entry rate and metabolic handling of LTC4 in the human circulation --;Genetic polymorphisms of 5-LO --;Leukotrienes and aspirin-intolerant asthma --;Leukotrienes in nocturnal asthma --;Leukotrienes and allergic asthma --;Inhibitors of leukotrienes: An overview --;The development of zafirlukast (Accolate®) and the Zeneca series of peptidyl-leukotriene receptor antagonists --;The development of zileuton (ZYFLO®) and the N-hydroxyurea class of 5-lipoxygenase inhibitors --;The development of BAY X 1005 and the Bayer series of leukotriene biosynthesis inhibitors --;The development of iralukast: A member of the Novartis series of cysteinyl leukotriene antagonists --;LTB4 receptor antagonists --;SmithKline Beecham pharmaceuticals' cysteinyl leukotriene receptor antagonists: Pranlukast (SB 205312; Ono-1078; Onon), Pobilukast (SK & F 104353) and SK & F 106203.
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| Abstract
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Many new antileukotriene drugs are now marketed as antiasthma drugs and represent the first new drugs in this field since the 1970s.
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| Subject
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Medicine.
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| LC Classification
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RM405.E358 1999
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| Added Entry
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Bengt Samuelsson
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Giancarlo Folco
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Robert C Murphy
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