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" The carbonic anhydrases : "
edited by W.R. Chegwidden, N.D. Carter, and Y.H. Edwards.
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BL
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| Record Number
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734472
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b554304
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| Main Entry
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edited by W.R. Chegwidden, N.D. Carter, and Y.H. Edwards.
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| Title & Author
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The carbonic anhydrases : : new horizons\ edited by W.R. Chegwidden, N.D. Carter, and Y.H. Edwards.
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| Publication Statement
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Basel ; Boston: Birkhäuser, [2000] ©2000
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| Series Statement
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EXS, 90.
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| Page. NO
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(xviii, 619 pages) : illustrations (some color)
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| ISBN
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303488446X
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: 3034895704
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: 9783034884464
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: 9783034895705
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| Contents
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Exordium: Remarks on the discovery of carbonic anhydrase --;to the carbonic anhydrases --;Evolution and distribution of the carbonic anhydrase gene families --;An overview of the distribution and function of carbonic anhydrase isozymes in mammals --;The membrane carbonic anhydrases: from CO2transport to tumour markers --;Carbonic anhydrase (CA)-related proteins (CA-RPs), and transmembrane proteins with CA or CA-RP domains --;Regulation of the CA 1, CA 2 and CA 3 genes --;Use of carbonic anhydrase II-deficient mice in uncovering the cellular location of membrane-associated isoforms --;X-ray crystallographic studies of mammalian carbonic anhydrase isozymes --;The catalytic mechanism of mammalian carbonic anhydrases --;Activation of carbonic anhydrase isozymes --;Active-site engineering of carbonic anhydrase and its application to biosensors --;Folding and stability of human carbonic anhydrase II --;Membrane transport and provision of substrates for carbonic anhydrase in vertebrates --;Respiratory and renal roles of carbonic anhydrase in gas exchange and acid-base regulation --;The roles of carbonic anhydrase in metabolism, cell growth and cancer in animals --;The roles of carbonic anhydrase in gustation, olefaction and chemical irritation --;Carbonic anhydrases in striated muscle --;Inherited deficiencies and activity variants of the mammalian carbonic anhydrases --;Carbonic anhydrase inhibition in ophthalmology: Carbonic anhydrase in cornea, lens, retina and lacrimal gland --;Carbonic anhydrase inhibition in ophthalmology: Aqueous humour secretion and development of sulphonamide inhibitors --;The design of new carbonic anhydrase inhibitors --;Roles of carbonic anhydrases in the alimentary tract --;Carbonic anhydrases in the nervous system --;Carbonic anhydrases in calcified tissues --;Carbonic anhydrases of higher plants: an overview --;Plant carbonic anhydrases: structure and mechanism --;Algal carbonic anhydrase --;Bacterial carbonic anhydrases --;Keeping pace with a fast enzyme: steps and missteps --;Carbonic anhydrase research: A clinical perspective, past and future.
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| Abstract
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Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer.
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| Subject
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Carbonic Anhydrase Inhibitors.
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| Subject
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Carbonic anhydrase.
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| Subject
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Carbonic Anhydrases.
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| LC Classification
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QP613.C37E358 9999
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| Added Entry
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N D Carter
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W R Chegwidden
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Y H Edwards
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