| Document Type
|
:
|
BL
|
| Record Number
|
:
|
736700
|
| Doc. No
|
:
|
b556565
|
| Main Entry
|
:
|
edited by Clive P. Page, Peter J. Barnes.
|
| Title & Author
|
:
|
Pharmacology of Asthma\ edited by Clive P. Page, Peter J. Barnes.
|
| Publication Statement
|
:
|
Berlin, Heidelberg: Springer Berlin Heidelberg, 1991
|
| Series Statement
|
:
|
Handbook of experimental pharmacology, 98.
|
| Page. NO
|
:
|
(xvii, 320 pages 45 illustrations)
|
| ISBN
|
:
|
364275855X
|
|
|
:
|
: 9783642758553
|
| Contents
|
:
|
1 The Pathology of Asthma: An Overview --;A. Introduction --;B. Methods to Investigate the Pathology of Human Asthma --;C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks --;D. Bronchial Epithelial Inflammation During an Asthma Attack --;E. Epithelial Regeneration --;F. Airway Smooth Muscle --;G. Bronchial Glands --;H. Neural Pathways --;I. Nerves and Other Airway Structures --;J. Bronchial Circulation --;K. Leakage of the Bronchial Vascular Bed in Patients with Asthma --;L. Conclusion --;References --;2 The Contribution of Inflammatory Cells to the Pathogenesis of Asthma --;A. Inflammation and Inflammatory Cells --;B. Pathological Evidence for Inflammation in Asthma --;C. Microvascular Leakage --;D. Neutrophils --;E. Eosinophils --;F. Mast Cells and Basophils --;G. Monocytes and Macrophages (Mononuclear Phagocytes) --;H. Platelets --;I. Lymphocytes --;J. Concluding Comments --;References --;3 Inflammatory Mediators --;A. Introduction --;B. Histamine --;C. Cyclooxygenase Products --;D. Lipoxygenase Products --;E. PAF --;F. Kinins --;G. Adenosine --;H. Complement --;I. Serotonin --;J. Chemotactic Factors --;K. Oxygen Radicals --;L. Conclusions --;References --;4 Pharmacology of Airway Smooth Muscle --;A. Introduction --;B. E/C Coupling Mechanisms --;C. E/C Uncoupling Mechamisms --;D. Future Trends in the Development of Bronchodilator Drugs --;References --;5 Neural Mechanisms in Asthma --;A. Introduction --;B. Cholinergic Mechanisms --;C. Adrenergic Mechanisms --;D. NANC Nerves and Neuropeptides --;E. Conclusions --;References --;6 Pharmacology and Therapeutics of?-Adrenoceptor Agonists --;A. Introduction --;B. The Molecular Nature of the?-Adrenoceptor and Its Relationship to Adenylate Cyclase --;C. Density and Distribution of?-Adrenoceptors in the Lung --;D. Therapeutic Sites of Action --;E. The Status of?-Adrenoceptor Function in Asthma --;F. The Importance of?2-Adrenoceptor Selectivity and Efficacy --;G. Adverse Reactions to?-Adrenoceptor Agonists --;H. Therapeutic Actions of?-Agonists --;I. Concluding Remarks --;References --;7 Pharmacology of Anti-Asthma Xanthines --;A. Introduction --;B. Clinical Use --;C. Mode of Action of Xanthines --;D. Conclusion --;References --;8 Glucocotricosteroids in Asthma --;A. Mechanism of Action of Glucocorticosteroids --;B. Clinical Use --;C. Future Developments --;References --;9 Pharmacology of Prophylactic Anti-Asthma Drugs --;A. Cromoglycate and Nedocromil --;B. Ketotifen --;C. Pharmacological Analysis --;References --;10 Pathophysiology and Pharmacology of Aspirin-Induced Asthma --;A. Introduction --;B. Definition and Main Clinical Features --;C. Pathogenesis.
|
| Abstract
|
:
|
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 . . . . . . . . . . . . . . . Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 . . . . .
|
| Subject
|
:
|
Human physiology.
|
| Subject
|
:
|
Immunology.
|
| Subject
|
:
|
Medicine.
|
| LC Classification
|
:
|
QP905.E358 1991
|
| Added Entry
|
:
|
C P Page
|
|
|
:
|
Peter J Barnes
|