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" Atherosclerosis Drug Discovery "
edited by Charles E. Day.
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BL
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| Record Number
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737080
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b556947
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| Main Entry
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edited by Charles E. Day.
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| Title & Author
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Atherosclerosis Drug Discovery\ edited by Charles E. Day.
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| Publication Statement
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Boston, MA: Springer US : Imprint : Springer, 1976
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| Series Statement
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Advances in experimental medicine and biology, 67.
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| ISBN
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146144618X
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: 147579309X
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: 9781461446187
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: 9781475793093
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| Contents
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Section 1 Primate Models.- A Model for Therapeutic Interventions on Established Coronary Atherosclerosis in a Nonhuman Primate.- The Nonhuman Primates as Models for Studying Human Atherosclerosis: Studies on the Chimpanzee, the Baboon and the Rhesus Macacus.- Phylogenetic Variability of Serum Lipids and Lipoproteins in Nonhuman Primates Fed Diets with Different Contents of Dietary Cholesterol.- The Baboon in Atherosclerosis Research: Comparison with Other Species and Use in Testing Drugs Affecting Lipid Metabolism.- The Fine Structure of Nonatherosclerotic Intimal Thickening, of Developing, and of Regressing Atherosclerotic Lesions at the Bifurcation of the Left Coronary Artery.- Apo-Lipoprotein Localization in Human Atherosclerotic Arteries.- Section 2 Rabbit Models.- Rabbits as a Model for the Study of Hyperlipoproteinemia and Atherosclerosis.- Seasonal Variations in Severity of Experimental Atherosclerosis in Rabbits.- Study of Drugs Affecting Cholesterol-Induced Atherosclerosis in Rabbits.- Turnover and Aortic Uptake of Very Low Density Lipoproteins (VLDL) from Hypercholesteremic Rabbits as a Model for Testing Antiatherosclerotic Compounds.- Evaluation of Permeability Parameters (Influx, Efflux and Volume of Distribution) of Arterial Wall for LDL and Other Proteins.- Oxygen Diffusion and Atherosclerosis.- Section 3 Rodent Models.- High Volume Screening Procedures for Hypobetalipoproteinemic Activity in Rats.- Biological Activity of a Hypobetalipoproteinemic Agent.- Nonisotopic Method for Estimating Cholesterogenesis in the Rat.- Cholesterol Metabolism in Rats Sensitive to High Cholesterol Diet.- Importance of Sex and Estrogens in Amelioration of Lethal Circulatory Stress Reactions: Relationship to Microcirculatory and Reticuloendothelial System Function.- Inbred Mice and Their Hybrids as an Animal Model for Atherosclerosis Research.- Diet Induced Hypercholesterolemia in the Diabetic and Non-Diabetic Chinese Hamster.- Section 4 Avian Models.- Animal Model for Experimental Atherosclerosis Produced by Selective Breeding of Japanese Quail.- Morphologic Observations on Experimental Atherosclerosis in SEA Japanese Quail.- A Mechanism for Lipid Accumulation and Central Necrosis in Fibrous Plaques.- The Influence of Some Dietary Factors and/or Treadmill Exercise on Rat and Chicken Tissue Lipids and Serum Lipoproteins.- Section 5 Tissue Culture.- Effects of Cholesterol Derivatives on Sterol Biosynthesis.- Mechanism of Inhibition of Cholesterol Uptake by the Arterial Wall.- Lipoprotein Uptake and Degradation by Cultured Human Arterial Smooth Muscle Cells.- The Removal of Cellular Lipids from Landschutz Ascites Cells and Smooth Muscle Cells in Culture.
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Cardiology.
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Medicine.
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| LC Classification
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RC692.E358 1976
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| Added Entry
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Charles E Day
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