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" Aminoglycoside Antibiotics "
edited by Hamao Umezawa, Irving R. Hooper.
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BL
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| Record Number
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738433
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b558346
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| Main Entry
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edited by Hamao Umezawa, Irving R. Hooper.
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| Title & Author
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Aminoglycoside Antibiotics\ edited by Hamao Umezawa, Irving R. Hooper.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1982
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| Series Statement
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Handbook of Experimental Pharmacology, Continuation of Handbuch der experimentellen Pharmakologie,, 62.
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| ISBN
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364268579X
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: 3642685811
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: 9783642685798
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: 9783642685811
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| Contents
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1 The Naturally Occurring Aminoglycoside Antibiotics --;A. Introduction --;B. Aminoglycoses and Noncyclitol Aminoglycosides --;C. Aminocyclitol Aminoglycosides Containing Streptamine, 2-Deoxystreptamine, or Their Derivatives --;D. Aminoglycosides with Cyclitol Aglycones Other than Streptamine or 2-Deoxystreptamine --;References --;2 Total Synthesis and Chemical Modification of the Aminoglycoside Antibiotics --;A. Introduction --;B. Several Reactions and Methods Generally Useful for the Synthesis of Aminoglycoside Antibiotics --;C. Total Synthesis and Modification of Aminoglycoside Antibiotics --;References --;3 Biosynthesis and Mutasynthesis of Aminoglycoside Antibiotics --;A. Introduction --;B. Biosynthesis of Major Aminoglycosides --;C. Mutational Biosynthesis (Mutasynthesis) --;D. Conclusion --;References --;4 Antibacterial Activity of Aminoglycoside Antibiotics --;A. Introduction --;B. Drug Resistance Plasmids --;C. Resistance Patterns of Bacteria --;D. Bacterial Strains Resistant to Aminoglycoside Antibiotics --;E. Conclusion --;References --;5 Mechanism of Action of Aminoglycoside Antibiotics --;A. The Effects on Bacterial Cells and Their Components --;B. Effects on Mammalian or Eukaryotic Cells and Their Components --;C. Peptide Antibiotics Showing Similar Mechanisms of Inhibition of Ribosomal Functions --;D. Discussion --;E. Summary --;References --;6 Mechanisms of Resistance to Aminoglycoside Antibiotics --;A. Introduction --;B. Biochemical Mechanisms of Resistance --;C. Derivatives Active Against Resistant Strains --;D. Conclusion --;References --;7 Toxicology and Pharmacology of Aminoglycoside Antibiotics --;A. Introduction --;B. Nephrotoxicity of Aminoglycosides --;C. Ototoxicity of Aminoglycosides --;D. Acute Lethal Toxicity of Aminoglycosides --;E. Correlation Between Chemical Structure and LD50 Values of Aminoglycosides --;F. General Pharmacology of Aminoglycosides --;G. Pharmacokinetics --;References.
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| Subject
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Medicine.
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Pharmacy.
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Toxicology.
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Hamao Umezawa
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Irving R Hooper
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With contributions by numerous experts
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