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" Therapeutic Antibodies "
edited by John Landon, Tim Chard.
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BL
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738539
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b558452
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| Main Entry
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edited by John Landon, Tim Chard.
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| Title & Author
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Therapeutic Antibodies\ edited by John Landon, Tim Chard.
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| Publication Statement
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London: Springer London, 1995
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(xii, 231 pages 17 illustrations)
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| ISBN
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1447119371
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: 9781447119371
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| Contents
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1 An Introduction to the Clinical Applications of Antibodies --;History --;Types and Sources of Antibodies --;Diagnostic Applications --;Therapeutic Applications --;Potential Side-Effects --;Anticipated Developments and Conclusions --;References --;2 Biology of the Immune Response --;Innate Immune System --;Adaptive Immunity --;A Typical Immune Response --;Immunoglobulin Structure and Function --;References --;3 Antibody Production in the Hen --;Summary --;Background --;Comparison of Avian and Mammalian Antibody Production --;Uses of Avian Antibodies --;Alternatives to Avian Antibodies for Therapy --;References --;4 Catalytic Antibodies --;Catalysis via Transition-State Complementarity --;Antibody-Catalysed Hydrolysis of Labile Esters --;Hydrolysis of More-Stable Compounds --;Catalysis via Other Strategies --;Catalysis of Other Types of Reaction --;Polyclonal Catalytic Antibodies --;Developing Therapeutic Catalytic Antibodies --;Conclusion --;References --;5 Immunotherapy for Drug Toxicity --;Digoxin --;Colchicine --;Tricyclic Antidepressants --;References --;6 Therapeutic Antibodies to Snake Venoms --;History --;Standard Methods of Antivenom Production --;Different Types of Available Antivenoms --;Antivenom Reactions --;Methods of Antivenom Potency Assessment --;Recent Developments in Antivenom Production --;Conclusions --;References --;7 Therapeutic Antibodies to Tumours --;Cell Surface Targets for Antibody Therapy --;Biodistribution of Antibodies --;Therapeutic Strategies --;Limitations of Antibody Therapy --;Conclusions --;References --;8 Therapeutic Antibodies to Microorganisms --;Antibody Preparations Available for Prophylaxis and Treatment of Infections --;Applications of IM IgG Preparations for Prophylaxis of Viral Infection --;Applications of IVIG Therapy --;Use of IVIG Preparations for Prevention and Treatment of Specific Infection --;Conclusion --;References --;9 Immunological Therapy of Endotoxaemia: Anti-endotoxin Antibodies --;The Role of Endotoxin in Sepsis --;Endotoxin: Relationship of Structure to Function --;Approaches to Endotoxin Antagonism --;Mechanism of Anti-endotoxin Antibody Action --;The Use of Anti-core Antibodies --;Impact of Anti-core Antibody Class and Titre on Efficacy --;Prospective Studies of Human Polyclonal Core Antiserum --;Studies with Anti-core/ Lipid A Monoclonal Antibodies --;Impact of Anti-endotoxins on Cytokine Generation in Human Sepsis --;Advantages and Limitations of Anti-endotoxin Antibodies --;Summary --;References --;10 Cytokine Antibodies and Antagonists in the Treatment of Sepsis --;Toxin Initiation of Sepsis --;Properties of TNF, IL-1, IL-6 and their Receptors --;Cytokine Interactions in Inflammation --;Evidence that Cytokines are Involved in Sepsis --;Therapeutic Strategies --;Summary --;References.
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| Abstract
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Several aspects of clinical medicine are poised on the edge of a new era with the introduction of therapeutic antibodies. This volume is aimed at all clinicians involved with this form of treatment, especially accident and emergency physicians, clinical immunologists, and pharmacologists.
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Immunology.
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Internal medicine.
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Medicine.
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| LC Classification
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RM282.I44E358 1995
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| Added Entry
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John Landon
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Tim Chard
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