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" Ataxia-Telangiectasia "
edited by Richard A. Gatti, Robert B. Painter.
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BL
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| Record Number
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738608
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b558521
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| Main Entry
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edited by Richard A. Gatti, Robert B. Painter.
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| Title & Author
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Ataxia-Telangiectasia\ edited by Richard A. Gatti, Robert B. Painter.
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| Publication Statement
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Berlin, Heidelberg: Springer Berlin Heidelberg, 1993
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| Series Statement
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NATO ASI series., Series H,, Cell biology ;, 77.
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| ISBN
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3642782787
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: 3642782809
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: 9783642782787
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: 9783642782800
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| Contents
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I. Introduction --;Brief Historical Overview --;II. Isolation of A-T Gene(S) --;Cloning and characterization of a candidate gene for A-T complementation Group D --;Precise localization of a gene responsible for ataxiatelangiectasia on chromosome 11q --;How many A-T genes? --;Isolation of human cDNAs that complement the ataxiatelangiectasia phenotype in cultured fibroblasts --;Complementation of the cellular A-T phenotype by gene transfer --;Use of microcell hybrids for analysis of the 11q23 region and improved localization of the A-T Group A/C genes --;AT-like radiosensitive rodent cell mutants: an alternative approach to the isolation of the A-T gene(s) --;III. A-T Heterozygotes and Complementation --;Identification of A-T heterozygotes --;Correction of post-gamma ray DNA repair deficiency in ataxiatelangiectasia complementation group A fibroblasts by cocultivation with normal fibroblasts --;The A-T gene does not make a major contribution to familial breast cancer --;Mammography screening for A-T heterozygotes --;IV. Defining the A-T Defect --;Lymphoid V(D)J recombination: accessibility and reaction fidelity in normal and ataxia-telangiectasia cells --;Murine scid cells and human ataxia-telangiectasia cells complement each other's radiosensitivity --;Ataxia-telangiectasia: defective in a p53-dependent signal transduction pathway --;DNA recombination in the transgenic mouse brain --;V. A-T Variants --;Clinical variants of ataxia-telangiectasia --;Epidemiology of ataxia-telangiectasia in Italy --;Epidemiology of ataxia-telangiectasia in Costa Rica --;Clinical and cellular heterogeneity in ataxia-telangiectasia --;VI. Overviews --;Biochemical defects in ataxia-telangiectasia --;Radiobiology of ataxia-telangiectasia --;Treatment of ataxia-telangiectasia.
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| Abstract
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Proceedings of the NATO Advanced Research Workshop on Ataxia-Telangiectasia, held at Newport Beach, CA, USA, May 17-20, 1992
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Human genetics.
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Medicine.
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Oncology.
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Richard A Gatti
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Robert B Painter
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| Parallel Title
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Proceedings of the NATO Advanced Research Workshop on Ataxia-Telangiectasia, held at Newport Beach, CA, USA, May 17-20, 1992
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