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BL
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| Record Number
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742353
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| Doc. No
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b562300
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| Main Entry
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edited by David G. Watson.
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| Title & Author
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Pharmaceutical chemistry\ edited by David G. Watson.
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| Publication Statement
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Edinburgh : Churchill Livingstone, ©2011.
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| Series Statement
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Online access with purchase: Elsevier Clinical Key.
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| Page. NO
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(ix, 641 pages) : illustrations
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| ISBN
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070204850X
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: 9780702048500
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| Contents
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1 Bond type and bond strength; 2 Hydrocarbons: alkanes, alkenes, aromatics and alkylhalides; 3 Amines; 4 Neutral and acidic nitrogen compounds; 5 Oxygen- and sulphur-containing functional groups; 6 Protein structure and its relevance to drug action; 7 DNA structure and its importance to drug action; 8 Drug absorption, distribution, metabolism and excretion; 9 Structure, activity and drug design; 10 Drugs affecting the adrenergic system; 11 Drugs exerting non-adrenergic effects on cardiac output and vascular tone; 12 Drugs interacting with mammalian enzymes; 13 Central nervous system depressants; 14 Analgesics; 15 Local anaesthetics; 16 Anti-cholinergic agents; 17 Anti-histamine drugs ; 18 CNS stimulants and CNS-active drugs affecting the serotonergic system; 19 Drugs affecting haemostasis and thrombosis; 20 Drugs affecting the endocrine system; 21 Anticancer drugs; 22 Antimicrobial chemotherapy: A. Antibiotics. B. Antituberculosis drugs; 23 Antiviral drugs; 24 Antifungal chemotherapy; 25 Antiparasitic drugs; 26 Vitamins and minerals; 27 Biotechnologically produced products; 28 Drug and gene delivery systems; 29 Alcohol.
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| Abstract
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This new book, from the editor of the highly successful <i>Pharmaceutical Analysis</i>, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market and more on the drugs currently in use. The emphasis in the book is on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. Important physicochemical properties include pKa and partition coefficient and the properties of the structu.
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| Subject
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Pharmaceutical chemistry.
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| LC Classification
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RS403.E358 2011
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| Added Entry
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David G Watson
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