|
" Transporters as drug carriers : "
edited by Gerhard Ecker and Peter Chiba.
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
743761
|
| Doc. No
|
:
|
b563709
|
| Main Entry
|
:
|
edited by Gerhard Ecker and Peter Chiba.
|
| Title & Author
|
:
|
Transporters as drug carriers : : structure, function, substrates\ edited by Gerhard Ecker and Peter Chiba.
|
| Publication Statement
|
:
|
Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], 2009
|
| Series Statement
|
:
|
Methods and principles in medicinal chemistry, v. 44.
|
| Page. NO
|
:
|
(xx, 429 pages) : illustrations (some color)
|
| ISBN
|
:
|
3527627421
|
|
|
:
|
: 352762743X
|
|
|
:
|
: 9783527627424
|
|
|
:
|
: 9783527627431
|
| Contents
|
:
|
Transporters as Drug Carriers: Structure, Function, Substrates; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Human Transporter Families --; Structure, Function, Physiology; 1 The ABC Transporters: Structural Insights into Drug Transport; 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters; 3 Organic Anion Transporting Polypeptides (Oatps/OATPs); 4 CNS --; Transporters as Drug Targets; Part Two: Drug Transport in Microorganisms and Fungi; 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects.
|
| Abstract
|
:
|
This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the foundations for understanding and investigat.
|
| Subject
|
:
|
Drug carriers (Pharmacy)
|
| Subject
|
:
|
Drug resistance.
|
| Subject
|
:
|
Drugs -- Physiological transport.
|
| LC Classification
|
:
|
QP552.C34E358 2009
|
| Added Entry
|
:
|
Gerhard Ecker
|
|
|
:
|
Peter Chiba
|
| |