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" Macrophage as therapeutic target. "
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BL
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| Record Number
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750226
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b570185
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| Title & Author
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Macrophage as therapeutic target.
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| Publication Statement
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[Place of publication not identified] : Springer, 2013
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| ISBN
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3642557422
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: 9783642557422
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| Contents
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Preface.- Section I: General.- 1. The macrophage as a validated pharmaceutical target.2. Transcription factors that regulate macrophage development & function.3. Exploitation of macrophage clearance functions in vivo.4. Reaching the macrophage - routes of delivery.5. Antigen presenting cells & vaccine design.6. Macrophage-specific gene targeting in vivo.- Section II: Macrophage targets in inflammation.- 7. Integrins of macrophage & macrophage-like cells.8. Purinergic receptors.9. Macrophage lipid uptake & foam cell formation.10. Dietary fatty acids and macrophages.11. Macrophages as therapeutic targets in lysosomal storage disorders.12. Nuclear receptors as regulators of macrophage homeostasis & function.13. Relationships between reactive oxygen species & reactive nitrogen oxide species produced by macrophages.14. Proteases.15. Targeting the chemokine system.16. Antimicrobial peptides.17. Macrophage phospholipid products.- Section III: Modulation of specialised macrophage activities.- 18. Dendritic cells versus macrophages as antigen presenting cells; common and unique features.19. The osteoclast .20. Macrophages in the central and peripheral nervous system.21. Innate recognition of viruses by macrophage and related receptors: potential ligands for antiviral agents.22. Macrophages & Mycobacterium tuberculosis.23. Detection & control of fungi by macrophages: the role of carbohydrates and antifungal agents.
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