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" Protein Complexes that Modify Chromatin "
edited by J.L. Workman.
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BL
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750227
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b570186
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| Main Entry
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edited by J.L. Workman.
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| Title & Author
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Protein Complexes that Modify Chromatin\ edited by J.L. Workman.
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| Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint : Springer, 2003
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| Series Statement
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Current topics in microbiology and immunology, 274.
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(XII, 296 pages 38 illustrations, 6 illustrations in color.)
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| ISBN
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3540442081
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: 3642557473
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: 3642629091
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: 9783540442080
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: 9783642557477
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: 9783642629099
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| Contents
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Nucleosome assembly and remodeling --; Chromatin Proteins are determinants of centromere function --; HP1 complexes and heterochomatin assembly --; SMC protein complexes and the maintenance of chromosome integrity --; Selective gene regulation by SWI/SNF-related chromatin remodeling factors --; The SWI/SNF family of ATP-dependent chromatin remodelers: similar mechanisms for diverse functions --; Changing the DNA landscape: putting a SPN on Chromatin --; The MYST family of histone acetyltransferases --; N-CoR-HDAC corepressor complexes: roles in transcriptional regulation by nuclear receptors --; The NuRD complex: linking histone modification to nucleosome remodeling --; Subject index.
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| Abstract
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Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobilize nucleosomes or stabilize nucleosomes. A wide variety of such complexes have now been described. Some are abundant and may play global roles, others are more rare and specialized for functions at discreet loci. Several complexes share biochemical activities and genetic studies suggest overlapping functions. Many components of these complexes were first revealed in genetic screens, while others were discovered by novel biochemical approaches. This volume of Current Topics in Microbiology and Immunology reviews a wide variety of protein complexes that modify chromatin.
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Human genetics.
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Medicine.
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| Added Entry
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J L Workman
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