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" Shock, Sepsis, and Organ Failure : "
edited by Günther Schlag, Heinz Redl.
Document Type
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BL
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Record Number
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751124
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Doc. No
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b571083
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Main Entry
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edited by Günther Schlag, Heinz Redl.
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Title & Author
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Shock, Sepsis, and Organ Failure : : Scavenging of Nitric Oxide and Inhibition of its Production\ edited by Günther Schlag, Heinz Redl.
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Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg, 1999
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Page. NO
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(xiv, 293 pages)
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ISBN
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3642586309
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: 9783642586309
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Contents
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From the Contents: Inhibition of the Overproduction of Nitric Oxide in Septic Shock Using NG-Methyl-L-Arginine --; Clinical Studies with 546C88 --; Norepinephrine Versus L-NMMA in Hyperdynamic Septic Shock --; Roles for Induced Nitric Oxide in Endotoxic and Hemorrhagic Shock --; Inducible NOS and Other Novel Mediators of Inflammation in Brain Trauma --; Cytokine Control of Nitric Oxide Production: Therapeutic Possibilities --; Inhibition of Nitric Oxide Synthases by the 4-Amino Analogue of Tetrahydrobiopterin --; Effect of Nitric Oxide Inhibitors and Hemoglobin in Sepsis.
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Abstract
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At the Sixth Wiggers Bernard Conference, a group of scientists from various fields discussed new findings relating to nitric oxide synthase inhibitor in shock, sepsis, and organ failure. This meeting was dedicated to the presentation and discussion of positive and negative findings related to the use of NOS inhibitors, the issue of specific and non-specific inhibitors and the role of nitric oxide-oxygen radical interactions. Both experimental and clinical data were presented in the trauma and sepsis field. With appropriate dosing and timing the use of NOS inhibitors seems to be beneficial at least in severe sepsis situations, but some inhibitors and overdosing can be potentially dangerous.
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Subject
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Anesthesiology.
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Subject
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Emergency medicine.
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Subject
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Medicine.
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LC Classification
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RC182.S4E358 1999
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Added Entry
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Günther Schlag
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Heinz Redl
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