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" Mechanisms of drug interactions "
contributors, G.L. Amidon [and others] ; editors, P.F. D'Arcy, J.C. McElnay, and P.G. Welling.
Document Type
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BL
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Record Number
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751720
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Doc. No
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b571679
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Main Entry
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contributors, G.L. Amidon [and others] ; editors, P.F. D'Arcy, J.C. McElnay, and P.G. Welling.
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Title & Author
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Mechanisms of drug interactions\ contributors, G.L. Amidon [and others] ; editors, P.F. D'Arcy, J.C. McElnay, and P.G. Welling.
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Publication Statement
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Berlin ; New York : Springer, ©1996.
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Series Statement
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Handbook of experimental pharmacology, v. 122.
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Page. NO
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(xvi, 363 pages) : illustrations
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ISBN
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3642610153
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: 9783642610158
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Contents
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1 Introduction --; A.A Widening Problem --; B. Pharmacokinetic Drug Interactions --; C. Pharmacodynamic Drug Interactions --; D. Comment --; References --; Section I: Pharmacokinetic Drug Interactions --; 2 Drug Interactions in The Gastrointestinal Tract and Their Impact on Drug Absorption and Systemic Availability: A Mechanistic Review --; 3 Drug-Food Interactions Affecting Drug Absorption --; 4 Drug Interactions at Plasma and Tissue Binding Sites --; 5 Drug Interactions and Drug-Metabolising Enzymes --; 6 Drug Interactions Involving Renal Excretory Mechanisms --; Section II: Pharmacodynamic Drug Interactions --; 7 Drug-Drug Interactions at Receptors and Other Active Sites --; 8 Synergistic Drug Interactions --; 9 In Vitro Drug Interactions --; 10 Age and Genetic Factors in Drug Interactions --; 11 Drugs Causing Interference with Laboratory Tests --; 12 Drug Interactions with Herbal and Other Non-orthodox Remedies.
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Abstract
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This book draws from leaders who are active in the various disciplines to provide a broad spectrum of information on mechanisms and clinical impact of drug interactions - of critical importance in this age of multiple-drug therapy. It deals with mechanisms of in vitro and in vivo, drug-drug, drug-food and drug-herbal interactions and those that cause drugs to interfere with diagnostic laboratory tests. It describes all aspects of drug interactions and their mechanisms ranging from those affecting drug absorption, metabolism, excretion and pharmacology and therapeutic activity, through those interactions affecting drug analysis. This volume will add much to that which is currently known about drug interactions and will directly enhance the safer use of medicines.
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Subject
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Drug interactions.
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Subject
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Drug Interactions.
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Subject
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Geneesmiddeleninteracties.
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LC Classification
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QP905.C668 1996
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Added Entry
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Gordon L Amidon
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J C McElnay
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P F D'Arcy
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Peter G Welling
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