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" Antigen Presentation "
edited by J. Lindsay Whitton.
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BL
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| Record Number
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753095
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b573056
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| Main Entry
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edited by J. Lindsay Whitton.
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| Title & Author
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Antigen Presentation\ edited by J. Lindsay Whitton.
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| Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg, 1998
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| Series Statement
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Current topics in microbiology and immunology, 232.
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| Page. NO
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(x, 244 pages 11 illustrations, 3 illustrations in color.)
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| ISBN
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354063813X
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: 3642720455
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: 9783540638131
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: 9783642720451
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| Contents
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(Overview) --; How Do Endogenous Proteins Become Peptides and Reach the Endoplasmic Reticulum --; Molecular Requirements for Assembly and Intracellular Transport of Class I Major HCM --; Peptide-Major HC Class I Complex --; Immune Response of €2-Microglobulin-Deficient Mice to Pathogens --; CNS Neurons --; Suppression of MHC Class I Antigen Presentation by Human-Adenoviruses --; Herpesvirus Evastion of the Immune System --; Intracellular Transport of Molecules Engaged in the Presentation of Exogenous Antigen.
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| Abstract
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Antigen presentation is central to the immune response, and is instrumental in ensuring that the response mounted is that best suited to the eradication of the particular microbe faced. In this volume, experts in the field provide state-of-the-art descriptions of the antigen presentation pathways. How do viruses disrupt these critical pathways, and to what effect? Do all tissues present antigen in the same way? If not, why? What are the consequences of dysfunctional antigen presentation, seen in certain genetic disorders? This book considers not only the molecular details, but also their relevance to the whole organism.
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| Subject
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Immunology.
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Medicine.
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Microbiology.
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| LC Classification
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QR1.E358 1998
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| Added Entry
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J Lindsay Whitton
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