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" Antiarrhythmic Drugs "
edited by E.M. Vaughan Williams.
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BL
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| Record Number
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753236
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b573197
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| Main Entry
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edited by E.M. Vaughan Williams.
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| Title & Author
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Antiarrhythmic Drugs\ edited by E.M. Vaughan Williams.
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| Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg, 1989
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| Series Statement
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Handbook of experimental pharmacology, 89.
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(xxix, 650 pages 113 illustrations)
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| ISBN
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3642736661
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: 9783642736667
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| Contents
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1 Cardiac Electrophysiology --; 2 Classification of Antiarrhythmic Actions --; 3 Acute and Chronic Animal Models of Cardiac Arrhythmias --; 4 Classification of Human Arrhythmias --; 5 Successes and Limitations of Antiarrhythmic Drug Therapy --; 6 Distinguishing Potentially Lethal from Benign Arrhythmias --; Antiarrhythmic Therapy --; Class I Agents --; 7 Subclassification of Class I Antiarrhythmic Drugs --; 8 Interaction of Class I Drugs with the Cardiac Sodium Channel --; 9 Clinical Use of Class Ia Antiarrhythmic Drugs --; 10 Clinical Use of Class Ib Antiarrhythmic Drugs --; 11 Clinical Use of Class Ic Antiarrhythmic Drugs --; Class II Agents --; 12a Arrhythmias in the Normal Human Heart --; 12b Adrenergic Arrhythmogenicity --; 13 Antiarrhythmic Properties of Beta-Adrenoceptor Blockade During and After Myocardial Infarction --; Class III Agents --; 14 Class III Antiarrhythmic Action --; 15 Amiodarone: Electropharmacologic Properties --; 16 Sotalol --; 17 Clofilium and Other Class III Agents --; Class IV Agents --; 18 Class IV Antiarrhythmic Agents: Utility in Supraventricular Arrhythmias and Their Proarrhythmic Potential --; Class V Agents --; 19 Specific Bradycardic Agents --; Other Therapies --; 20 Use of Adenosine as an Antiarrhythmic Agent --; 21 Physical and Surgical Treatment of Cardiac Arrhythmias --; Factors Involved in Arrhythmogenesis --; 22 Alpha-Adrenoceptors in Arrhythmogenesis --; 23 Adrenergic Arrhythmogenesis and the Long Q-T Syndrome --; 24a Effects of Cardiac Glycosides at the Cellular Level --; 24b Clinical Efficacy of Cardiac Glycosides for Arrhythmias --; 25 Eicosanoids and Arrhythmogenesis --; 26 Possible Role of Lipids and of Free Radicals in Arrhythmogenesis --; 27 Clinical and Pharmacological Characterization and Treatment of Potentially Malignant Arrhythmias of Chronic Chagasic Cardiomyopathy --; 28 Autonomic Mechanisms in Cardiac Rhythm and Arrhythmias --; Epilogue --; Epilogue.
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| Abstract
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This volume provides a much-needed bridge between clinical cardiology and basic science. The first section is concerned with cellular and clinical electrophysiology and with the classification of human cardiac arrythmias and of the modes of action of antiarrhythmic drugs. The next part deals with clinical pharmacology and provides a practical manual for cardiologists in the choice of drug regimes appropriate to each type of arrhythmia. The final section discusses various aspects of arrhythmogenesis including ischaemia, drug intoxication, congenital abnormality or previous pathology, and the possible involvement of autonomic receptors, cAMP, plasma fatty acids, prostanoids, or free radicles. As a whole, the designed volume offers a general survey of the origin and treatment of arrhythmias, while each chapter provides detailed specialized information. It will be a valuable source for all those seeking to understand the causes of, and to find remedies for, abnormalities of cardiac rhythm.
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Human physiology.
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Medicine.
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Toxicology.
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| LC Classification
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QP905.E358 1989
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E M Vaughan Williams
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| Parallel Title
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With contributions by numerous experts
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