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" Pathogenesis of Shigellosis "
edited by P.J. Sansonetti.
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BL
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| Record Number
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753670
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b573631
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| Main Entry
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edited by P.J. Sansonetti.
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| Title & Author
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Pathogenesis of Shigellosis\ edited by P.J. Sansonetti.
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| Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg, 1992
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| Series Statement
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Current topics in microbiology and immunology, 180.
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| Page. NO
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(x, 143 pages 15 illustrations)
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| ISBN
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3642772382
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: 9783642772382
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| Contents
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List of Contents --; Molecular and Cellular Biology of Shigella flexneri Invasiveness: From Cell Assay Systems to Shigellosis --; The Large Virulence Plasmid of Shigella --; Shigella Lipopolysaccharide: Structure, Genetics, and Vaccine Development --; Shiga Toxin: Biochemistry, Genetics, Mode of Action, and Role in Pathogenesis --; Environmental Regulation of Shigella Virulence --; Pathogenesis and Immunology in Shigellosis: Applications for Vaccine Development.
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| Abstract
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This book provides a state-of-the-art review of the various aspects of epithelial cell invasion by Shigellla. The molecular mechanism of entry intocells, intracellular growth and cell-to-cell spread are analysed as well as genetics, structure, and function of Shiga toxin and of the lipopolysaccharide (LPS). Finally, the applications of these studiesin the development of vaccines are reviewed. This exhaustive coverage was made possible by a collaborative effort of some of the major researchers in the field.
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| Subject
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Immunology.
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Medicine.
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Microbiology.
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| LC Classification
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QR1.E358 1992
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| Added Entry
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P J Sansonetti
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