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" Redirection of Th1 and Th2 Responses "
edited by Robert L. Coffman, Sergio Romagnani.
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BL
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| Record Number
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760341
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b580314
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| Main Entry
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edited by Robert L. Coffman, Sergio Romagnani.
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| Title & Author
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Redirection of Th1 and Th2 Responses\ edited by Robert L. Coffman, Sergio Romagnani.
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| Publication Statement
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Berlin, Heidelberg : Springer Berlin Heidelberg, 1999
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| Series Statement
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Current topics in microbiology and immunology, 238.
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| Page. NO
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(ix, 150 pages)
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| ISBN
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3662097095
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: 9783662097090
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| Contents
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The Stability and Reversibility of Th1 and Th2 Populations --; T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases --; Redirecting Th2 Responses in Allergy --; Interleukin-12: Basic Principles and Clinical Applications --; Redirecting Th1 and Th2 Responses in Autoimmune Disease --; Manipulation of the Th Responses of Oral Tolerance.
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| Abstract
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The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: - The mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production - The different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases - The prospects and strategies for therapeutic manipulation of Th1 and Th2 cells - The control of Th1 and Th2 responses by regulatory T cell subsets. The volume will give the reader a current view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
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Immunology.
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Medicine.
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Oncology.
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| LC Classification
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QR1.E358 1999
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| Added Entry
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Robert L Coffman
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S Romagnani
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