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" Prion diseases and copper metabolism : "
David R. Brown [editor].
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BL
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| Record Number
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768414
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| Doc. No
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b588401
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| Main Entry
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David R. Brown [editor].
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| Title & Author
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Prion diseases and copper metabolism : : BSE, scrapie and CJD research\ David R. Brown [editor].
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| Publication Statement
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Chichester : Horwood Publishing, 2002
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| Page. NO
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VIII, 250 p. : ill. ; 25 cm
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| ISBN
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189856387X
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: 9781898563877
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| Contents
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Copper - prion protein, molecular interactions; Effects of copper on the cellular trafficking and biochemical properties of the prion protein; Tracing the copper binding to the murine prion protein; Co-ordinate binding of copper to prion protein; Oxidative stress, metal ions and neurodegenerative disease; Near infrared spectroscopy for non-destructive analysis of prion protein isoforms; Prion and Alzheimer diseases; The copper binding domain of the amyloid precursor protein of Alzheimer's disease can modulate copper homeostasis and regulate amyloid AB production; Metals modulate the aggregation and neurotoxic properties of the prion peptide PrP106-126; Human CJD and trace elements; Metals and human prion disease; Disease progression and metal aberrations; Trace elements copper and manganese in soils; Future directions for copper and the prion protein.
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| LC Classification
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QR201.P737D385 2002
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| Added Entry
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David Robert Brown
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