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" Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance : "
edited by Eugenio E. Müller.
Document Type
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BL
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Record Number
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771254
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Doc. No
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b591247
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Main Entry
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edited by Eugenio E. Müller.
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Title & Author
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Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance : : From Basic to Clinical Research\ edited by Eugenio E. Müller.
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Publication Statement
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Milano : Springer Milan, 2003
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Page. NO
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(xii, 197 pages)
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ISBN
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8847020859
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: 9788847020856
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Contents
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LHRH/Somatostatin --; Chapter1 Twenty-five Years of Endocrine Oncology with Analogs of Hypothalamic Peptides: an Overview --; Chapter2 Analogs of Luteinizing Hormone-releasing Hormone in Benign Prostatic Hyperplasia and Advanced Renal Cell Carcinoma --; Chapter3 Luteinizing Hormone-releasing Hormone Antagonists in Gynecology --; Chapter4 Physiology and Pharmacology of Somatostatin and Its Receptors --; Chapter5 Investigation of LHRH Receptor Involvement in Melanoma Growth and Progression --; Somatostatin/GHRH/GH --; Chapter6 Cortistatin: Not Simply a Natural Somatostatin Analogue --; Chapter7 Antineoplastic and Antiangiogenic Actions of Somatostatin Analogs --; Chapter8 Somatostatin in Clinical Endocrinology --; Chapter9 Antagonists of Growth Hormone-releasing Hormone in Oncology --; Chapter10 GH Receptor Antagonists: Basic Knowledge and Clinical Perspectives --; Ghrelin and Ghrelin Mimetics (GHS) --; Chapter11 Hypothalamic Circuits Responsive to Ghrelin: Regulation by Leptin and Insulin --; Chapter12 Physiological Function of Growth Hormone Secretagogue Receptors in the Cardiovascular System --; Chapter13 Endocrine and Extraendocrine Activity of Ghrelin and the GHS: Basic Research --; Chapter14 Endocrine and Nonendocrine Actions of Ghrelin and GHS: State of the Art in Clinical Research --; Hormonal Treatments for Endocrine-Dependent Tumors --; Chapter15 Hormonal Treatments of Endocrine-Dependent Tumors: Preclinical Aspects --; Chapter16 Hormonal Treatment of Endocrine-Dependent Tumors: Clinical Considerations --; Chapter17 Letrozole in the Treatment of Advanced Breast Cancer.
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Abstract
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The book describes the ability of a series of endocrine-derived compounds, i.e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert a direct anti-neoplastic activity or to potentiate the activity of traditional chemotherapeutic agents on neuroendocrine and solid tumors. In addition, a new class of potent GH-releasers, GSHs/Ghrelin, endowed with important endocrine and extra-endcocrine action, is presented. Therefore, in addition to traditional chemotherapy, characterized by high toxicity and non-selective action on tumoral cells, the reader can find a new approach with more selective, less cytotoxic endocrine derived compounds.
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Subject
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Endocrinology.
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Subject
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Medicine.
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Subject
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Oncology.
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LC Classification
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RC280.E55E358 2003
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Added Entry
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Eugenio E Müller
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