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" AIDS Pathogenesis "
edited by Hanneke Schuitemaker, Frank Miedema.
Document Type
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BL
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Record Number
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776585
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Doc. No
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b596582
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Main Entry
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edited by Hanneke Schuitemaker, Frank Miedema.
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Title & Author
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AIDS Pathogenesis\ edited by Hanneke Schuitemaker, Frank Miedema.
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Publication Statement
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Dordrecht Springer Netherlands, 2000
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Series Statement
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Immunology and Medicine, 28
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Page. NO
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(XII, 284 p).
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ISBN
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9401706859
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: 9789401706858
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Abstract
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Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.
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Subject
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Immunology.
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Subject
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Infectious Diseases.
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Subject
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Virology.
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LC Classification
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RC607.A26E358 2000
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Added Entry
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Frank Miedema
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Hanneke Schuitemaker
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