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" Chapter 1 Cellular Mechanism for Targeting Heterochromatin Formation inDrosophila "


Document Type : BL
Record Number : 786425
Doc. No : b606440
Main Entry : Joel C Eissenberg
Title & Author : Chapter 1 Cellular Mechanism for Targeting Heterochromatin Formation inDrosophila\ Joel C Eissenberg
ISBN : 9780123748041
Abstract : Near the end of their 1990 historical perspective article “60 Years of Mystery,” Spradling and Karpen (1990) observe: “Recent progress in understanding variegation at the molecular level has encouraged some workers to conclude that the heterochromatization model is essentially correct and that position‐effect variegation can now join the mainstream of molecular biology.” In the 18 years since those words were written, heterochromatin and its associated position effects have indeed joined the mainstream of molecular biology. Here, we review the findings that led to our current understanding of heterochromatin formation in <ce:italic>Drosophila</ce:italic> and the mechanistic insights into heterochromatin structural and functional properties gained through molecular genetics and cytology.
Added Entry : Gunter Reuter Affiliation: Institute of Biology, Developmental Genetics, Martin Luther University Halle, Halle, Germany
: Joel C Eissenberg
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