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" Chapter 8: "
Ales Iglic Affiliation: Laboratory of Applied Physics, Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, SI-1000 Ljubljana, Slovenia
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BL
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786445
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b606460
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Ales Iglic Affiliation: Laboratory of Applied Physics, Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, SI-1000 Ljubljana, Slovenia
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Chapter 8: : Budding of Liposomes - Role of Intrinsic Shape of Membrane Constituents\ Ales Iglic Affiliation: Laboratory of Applied Physics, Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, SI-1000 Ljubljana, Slovenia
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9780123725059
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Corresponding author. Tel.: +386-1-4250-278; Fax: +386-1-4768-850
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The budding of phospholipid bilayer membrane is studied theoretically. The description starts from a single-constituent energy that reflects intrinsic shape of the constituent, and uses methods of statistical physics to obtain membrane free energy. The membrane free energy is minimized to yield the equilibrium shape and distribution functions of constituents. It is shown that two mechanisms based on internal degrees of freedom: in-plane orientational ordering of phospholipids in the narrow neck connecting the bud with the mother membrane and clustering of membrane inclusions in the budding region, are complementary mechanisms that promote budding of liposomes.
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Ales Iglic Affiliation: Laboratory of Applied Physics, Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, SI-1000 Ljubljana, Slovenia
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Veronika Kralj-Iglic Affiliation: Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Lipiceva 2, SI-1000 Ljubljana, Slovenia
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