| Document Type
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BL
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| Record Number
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802313
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| Doc. No
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b622384
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| Main Entry
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[edited by] Marek Pawlikowski.
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| Title & Author
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Somatostatin analogs in diagnostics and therapy\ [edited by] Marek Pawlikowski.
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| Publication Statement
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Austin, Tex.: Landes Bioscience, ©2007.
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| Series Statement
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Medical intelligence unit (Unnumbered : 2003)
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| Page. NO
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(1 volume).
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| ISBN
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1433713209
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: 1435602412
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: 1587064286
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: 9781433713200
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: 9781435602410
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: 9781587064289
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| Contents
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Physiology of somatostatin / Marek Pawlikowski --; Somatostatin receptors: distribution in normal tissues and transduction mechanisms / Gabriela Melen-Mucha and Slawomir Mucha --; Somatostatin analogs: lessons in functional complexity and receptor interactions / Michael D. Culler --; Somatostatin receptors in human tumors: in vitro studies / Marek Pawlikowski --; The treatment of acromegaly with somatostatin analogs / Nuria Sucunza, Jose Barahona, and Susan M. Webb --; The treatment of neuroendocrine tumors (NET) with somatostatin analogs / Beata Kos-Kudla --; Radiolabeled somatostatin analogs in the diagnosis and therapy of neuroendocrine tumors / Leszek Krelicki, Jolanta Kunikowska, and Marianna I. Bak --; Somatostatin analogs-new perspectives / Gabriela Melen-Mucha and Marek Pawlikowski.
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| Abstract
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Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide limits its therapeutic application. To overcome this limitation the long-lasting modified molecules (analogs) of somatostatin were synthesized. The present book provides comprehensive data on the application of somatostatin analogs in diagnostics and treatm.
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| Subject
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MEDICAL -- Biochemistry.
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| Subject
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Somatostatin -- analogs derivatives.
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| Subject
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Somatostatin.
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| LC Classification
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QP572.S59E358 2007
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| Added Entry
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M Pawlikowski
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