Addressing Limitations of a Spatially Sensitive Large-Area Ion Chamber for Real-Time Verification of...

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" Addressing Limitations of a Spatially Sensitive Large-Area Ion Chamber for Real-Time Verification of Intensity Modulated Radiation Therapy "
Xun Lin Islam, Mohammad K.; Heaton, Robert K.

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	803744
Doc. No	:	TL48545
Call number	:	‭1746693328;‮ ‬1604590‬
Main Entry	:	Jennings, Deserae
Title & Author	:	Addressing Limitations of a Spatially Sensitive Large-Area Ion Chamber for Real-Time Verification of Intensity Modulated Radiation Therapy\ Xun LinIslam, Mohammad K.; Heaton, Robert K.
College	:	University of Toronto (Canada)
Date	:	2015
Degree	:	M.H.Sc.
field of study	:	Biomedical Engineering
student score	:	2015
Page No	:	95
Note	:	Committee members: Coolens, Catherine; Dolan, Alf M.; Jaffray, David A.
Note	:	Place of publication: United States, Ann Arbor; ISBN=978-1-339-28229-9
Abstract	:	Lack of light transparency and overall thickness are limitations of a previously described spatially sensitive large-area ionization chamber used for real-time verification of radiation therapy beam delivery. The first limitation was addressed with investigation of a commercially available light transparent conductive glass plates as replacements for aluminum plates in the construction of the chamber. Resulting chamber produced expected spatial sensitivity, allowed the light field to be transmitted with 35% attenuation in intensity, and caused deviation of field position due to refraction up to 0.4 mm. The second limitation was investigated with a novel interleaved comb patterned electrode pairs. The pattern was ablated on a light transparent conductive glass plate and utilized for construction of an experimental prototype ionization chamber that was 35% thinner, light transparent, and produced a spatial sensitivity comparable to the original design. However, further refinement in the design and manufacturing process will be necessary to make a practical comb patterned ionization chamber pair.
Subject	:	Biomedical engineering; Biophysics; Oncology
Descriptor	:	Biological sciences;Applied sciences;Health and environmental sciences;Imrt;Large area ionization chamber;Light transparency;Online treatment verification;Real-time quality assurance
Added Entry	:	Islam, Mohammad K.; Heaton, Robert K.
Added Entry	:	Biomedical EngineeringUniversity of Toronto (Canada)