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" Surface engineered biosensors for the early detection of cancer "
Muhymin Islam
Iqbal, Samir
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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803816
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| Doc. No
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TL48619
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| Call number
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1761573953; 10003854
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| Main Entry
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Sadegh-Vaziri, Persheng
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| Title & Author
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Surface engineered biosensors for the early detection of cancer\ Muhymin IslamIqbal, Samir
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| College
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The University of Texas at Arlington
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| Date
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2015
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| Degree
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Ph.D.
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| field of study
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Electrical Engineering
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| student score
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2015
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| Page No
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187
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| Note
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Committee members: Butler, Donald; Ghosh, Santaneel; Kim, Young-Tae; Magnusson, Robert
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Place of publication: United States, Ann Arbor; ISBN=978-1-339-42914-4
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| Abstract
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Cancer commences in the building block of human body which is cells and in most of the cases remains silent at early stage. Diseases are only expressed at molecular and cellular level at primary stages. Recognition of diseases at this micro and nano level might reduce the mortality rate of cancer significantly. This research work aimed to introduce novel electronic biosensors for for identification of cancer at cellular level. The dissertation study focuses on 1) Label-Free Isolation of Metastatic Tumor Cells Using Filter Based Microfluidic device; 2) Nanotextured Polymer Substrates for Enhanced Cancer Cell Isolation and Cell Growth; 3) Nanotextured Microfluidic Channel for Electrical Profiling and Detection of Tumor Cells from Blood; and 4) Single Biochip for the Detection of Tumor Cells by Electrical Profile and Surface Immobilized Aptamer. Standard silicon processing techniques were followed to fabricate all of the biosensors. Nantoextruing and surface functionalizon were also incorporated to elevate the efficiency of the devices.
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| Subject
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Biomedical engineering; Electrical engineering; Nanotechnology
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| Descriptor
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Applied sciences;Aptamer;Biosensors;Cancer;Microfluidics;Nanotexture;Translocation profile
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| Added Entry
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Iqbal, Samir
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Electrical EngineeringThe University of Texas at Arlington
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